2-(丙酰基氨基)苯甲酸合成路线 （共 16 条）
反应条件
3 h; Heating / reflux;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2004/111014 A1, 2004 ;
Location in patent: Page/Page column 263-264 ;
WO 2004/111014 A1
反应条件
1: PCl3 2: aqueous HBr; acetic acid anhydride View Scheme
参考文献
Rani et al.
Journal of the Indian Chemical Society, 1953 , vol. 30, p. 331,333
反应条件
1: 30percent aq. NH3 / Ambient temperature 2: 2N aq. NaOH / Heating View Scheme
参考文献
Zentmyer; Wagner
Journal of Organic Chemistry, 1949 , vol. 14, p. 967,969, 977
反应条件
1: acetic anhydride / 140 °C 2: 3 h View Scheme
参考文献
Hermecz; Szilagyi; Orfi; Kokosi; Szasz
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 5 p. 1413 - 1420
反应条件
phosphorus trichoride in toluene
参考文献
Storelli, Stefania; Verdijk, Pauline; Verzijl, Dennis; Timmerman, Henk; Van De Stolpe, Andrea C.; Tensen, Cornelis P.; Smit, Martine J.; De Esch, Iwan J. P.; Leurs, Rob
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 11 p. 2910 - 2913
反应条件
phosphorus trichoride
参考文献
Kacker; Zaheer
Journal of the Indian Chemical Society, 1951 , vol. 28, p. 344
