(R)-2-[(boc-氨基)甲基]-3-甲基丁酸合成路线 （共 4 条）
反应条件
sodium hydroxide in 1,4-dioxane 16 h;
参考文献
Seebach, Dieter; Abele, Stefan; Gademann, Karl; Guichard, Gilles; Hintermann, Tobias; Jaun, Bernhard; Matthews, Jennifer L.; Schreiber, Juerg V.; Oberer, Lukas; Hommel, Ulrich; Widmer, Hans
Helvetica Chimica Acta, 1998 , vol. 81, # 5 p. 932 - 982
反应条件
1: 81 percent / TiCl4, Et3N / CH2Cl2 / 60 h / 0 °C 2: 77 percent / H2O2, LiOH*H2O / H2O; tetrahydrofuran / 1 h / 0 °C 3: 75 percent / aq. HCl / acetic acid / 48 h / Heating 4: 87 percent / aq. NaOH / dioxane / 16 h View Scheme
参考文献
Seebach, Dieter; Abele, Stefan; Gademann, Karl; Guichard, Gilles; Hintermann, Tobias; Jaun, Bernhard; Matthews, Jennifer L.; Schreiber, Juerg V.; Oberer, Lukas; Hommel, Ulrich; Widmer, Hans
Helvetica Chimica Acta, 1998 , vol. 81, # 5 p. 932 - 982
反应条件
1: 77 percent / H2O2, LiOH*H2O / H2O; tetrahydrofuran / 1 h / 0 °C 2: 75 percent / aq. HCl / acetic acid / 48 h / Heating 3: 87 percent / aq. NaOH / dioxane / 16 h View Scheme
参考文献
Seebach, Dieter; Abele, Stefan; Gademann, Karl; Guichard, Gilles; Hintermann, Tobias; Jaun, Bernhard; Matthews, Jennifer L.; Schreiber, Juerg V.; Oberer, Lukas; Hommel, Ulrich; Widmer, Hans
Helvetica Chimica Acta, 1998 , vol. 81, # 5 p. 932 - 982
反应条件
1: 75 percent / aq. HCl / acetic acid / 48 h / Heating 2: 87 percent / aq. NaOH / dioxane / 16 h View Scheme
参考文献
Seebach, Dieter; Abele, Stefan; Gademann, Karl; Guichard, Gilles; Hintermann, Tobias; Jaun, Bernhard; Matthews, Jennifer L.; Schreiber, Juerg V.; Oberer, Lukas; Hommel, Ulrich; Widmer, Hans
Helvetica Chimica Acta, 1998 , vol. 81, # 5 p. 932 - 982
