3,4-二氢吡啶[3,4-D]嘧啶-4-酮合成路线 （共 5 条）
参考文献
Warner-Lambert Company
Patent: US5654307 A1, 1997 ;
US 5654307 A
参考文献
WO2013/12915 A1, ;
Paragraph 00677 ;
WO 2013/012915 A1
参考文献
Chemische Berichte, , vol. 35, p. 2845
反应条件
thionyl chloride; N,N-dimethyl-formamide T=90°C; 1 h;
参考文献
Kudos Pharmaceuticals Ltd
Patent: US2006/199804 A1, 2006 ;
Location in patent: Page/Page column 30 ;
US 20060199804 A1
反应条件
1: 55 percent / pyridine / POCl3 / 1 h / Heating
2: NEt3 / benzene / 0.25 h / Heating
3: conc. HCl / acetic acid / 1 h / Heating
View Scheme
参考文献
Petric, Andrej; Tisler, M.; Stanovnik, Branko
Monatshefte fuer Chemie, 1983 , vol. 114, p. 615 - 624
