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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
191800-37-0
合成路线
(共 7 条)
92808-84-9
→
反应条件
191800-37-0
反应条件
C35H46N2O4PRu(1+)*F6P(1-); water; sodium hydrogencarbonate in tetrahydrofuran T=25°C; 12 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Kanbayashi, Naoya; Onitsuka, Kiyotaka
Angewandte Chemie - International Edition, 2011 , vol. 50, # 22 p. 5197 - 5199
1263474-81-2
→
反应条件
191800-37-0
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 0.25 h;
参考文献
Sumskaya, Yuliya G.; Swain, P. Whitney; Bergmeier, Stepehen C.; McMills, Mark C.; Priestley, Nigel D.; Wrighta, Dennis L.
Arkivoc, 2011 , vol. 2011, # 5 p. 144 - 166
86106-09-4
(R)-3-丁烯-1,2-二醇
+
58479-61-1
叔丁基二苯基氯硅烷
→
反应条件
191800-37-0
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in tetrahydrofuran T=0 - 20°C; Inert atmosphere; regioselective reaction;
参考文献
Stambasky, Jan; Kapras, Votech; Stefko, Martin; Kysilka, Ondrej; Hocek, Michal; Malkov, Andrei V.; Kocovsky, Pavel
Journal of Organic Chemistry, 2011 , vol. 76, # 19 p. 7781 - 7803
301670-77-9
→
反应条件
191800-37-0
反应条件
sodium hydroxide in methanol T=20°C; Hydrolysis; 2 h;
参考文献
Dallanoce, Clelia; De Amici, Marco; Carrea, Giacomo; Secundo, Francesco; Castellano, Sabrina; De Micheli, Carlo
Tetrahedron Asymmetry, 2000 , vol. 11, # 13 p. 2741 - 2751
58479-61-1
叔丁基二苯基氯硅烷
→
反应条件
191800-37-0
反应条件
1: 88 percent / Et3N; 4-dimethylaminopyridine / tetrahydrofuran / 20 °C 2: CALB / petroleum ether / 18 h / 20 °C 3: 2N aq. NaOH / methanol / 2 h / 20 °C View Scheme
参考文献
Dallanoce, Clelia; De Amici, Marco; Carrea, Giacomo; Secundo, Francesco; Castellano, Sabrina; De Micheli, Carlo
Tetrahedron Asymmetry, 2000 , vol. 11, # 13 p. 2741 - 2751
191800-36-9
→
反应条件
191800-37-0
反应条件
methanol; potassium carbonate in tetrahydrofuran 1 h; Ambient temperature; Yield given;
参考文献
Maeda, Mikiko; Okazaki, Fumiaki; Murayama, Mayumi; Tachibana, Yohko; Aoyagi, Yutaka; Ohta, Akihiro
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 6 p. 962 - 965
91376-49-7
→
反应条件
191800-37-0
反应条件
1: diethylazodicarboxylate, PPh3 / toluene / Ambient temperature 2: K3CO3, MeOH / tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Maeda, Mikiko; Okazaki, Fumiaki; Murayama, Mayumi; Tachibana, Yohko; Aoyagi, Yutaka; Ohta, Akihiro
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 6 p. 962 - 965