1: N,N-dimethyl acetamide / |Reflux 2: N-ethyl-N,N-diisopropylamine; pyridine / 20 °C 3: 1,10-phenanthroline; copper diacetate / N,N-dimethyl-formamide / 72 h / 20 °C 4: lithium hydroxide hydrate; water / tetrahydrofuran / 60 °C View Scheme

1: 1,10-phenanthroline; copper diacetate / N,N-dimethyl-formamide / 72 h / 20 °C 2: lithium hydroxide hydrate; water / tetrahydrofuran / 60 °C View Scheme

1: N-ethyl-N,N-diisopropylamine; pyridine / 20 °C 2: 1,10-phenanthroline; copper diacetate / N,N-dimethyl-formamide / 72 h / 20 °C 3: lithium hydroxide hydrate; water / tetrahydrofuran / 60 °C View Scheme

1: 1,10-phenanthroline; copper diacetate / N,N-dimethyl-formamide / 72 h / 20 °C 2: lithium hydroxide hydrate; water / tetrahydrofuran / 60 °C View Scheme