4-N-(2-胺乙基)-1-N-BOC-哌啶合成路线 （共 8 条）
反应条件
triethylamine in N-methyl-acetamide; methanol
参考文献
Aventis Pharma Deutschland GmbH
Patent: US6395737 B1, 2002 ;
反应条件
sodium hydroxide in methanol; water T=15 - 35°C; 37 h;
参考文献
Heterocycles, , vol. 76, # 2 p. 1219 - 1235
反应条件
potassium bisulfate in water T=20°C; 3 h;
参考文献
Bulletin of the Korean Chemical Society, , vol. 33, # 8 p. 2597 - 2602
反应条件
hydrazine hydrate in ethanol T=70°C;
参考文献
ChemMedChem, , vol. 9, # 4 p. 752 - 761
反应条件
1: toluene / 8 h / |Reflux 2: toluene / 3 h / 0 - 20 °C 3: potassium bisulfate / water / 3 h / 20 °C View Scheme
参考文献
Bulletin of the Korean Chemical Society, , vol. 33, # 8 p. 2597 - 2602
反应条件
1: 0.5 h / 0 - 20 °C / |Inert atmosphere; |Dean-Stark 2: water / isopropyl alcohol / 50 °C View Scheme
参考文献
Organic Process Research and Development, , vol. 9, # 1 p. 102 - 104
反应条件
1: toluene / 3 h / 0 - 20 °C 2: potassium bisulfate / water / 3 h / 20 °C View Scheme
参考文献
Bulletin of the Korean Chemical Society, , vol. 33, # 8 p. 2597 - 2602
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 70 °C 2: hydrazine hydrate / ethanol / 70 °C View Scheme
参考文献
ChemMedChem, , vol. 9, # 4 p. 752 - 761
