5-氯-2-甲基苯并恶唑合成路线 （共 23 条）
参考文献
International Journal of Mass Spectrometry, , vol. 345-347, p. 120 - 131
反应条件
1: hydrogenchloride; SnCl2·2H2O / 4.5 h 2: 1.5 h / |Reflux View Scheme
参考文献
International Journal of Mass Spectrometry, , vol. 345-347, p. 120 - 131
反应条件
1: nitric acid / 0.03 h / 16 °C 2: hydrogenchloride; SnCl2·2H2O / 4.5 h 3: 1.5 h / |Reflux View Scheme
参考文献
International Journal of Mass Spectrometry, , vol. 345-347, p. 120 - 131
反应条件
1: acetic acid anhydride / 100 °C 2: tin; hydrochloric acid 3: lagert sich spontan 4: beim Erhitzen ueber den Schmelzpunkt View Scheme
参考文献
American Chemical Journal, , vol. 32, p. 15
反应条件
1: tin; hydrochloric acid 2: lagert sich spontan 3: beim Erhitzen ueber den Schmelzpunkt View Scheme
参考文献
American Chemical Journal, , vol. 32, p. 15
反应条件
T=220 - 250°C; im Rohr;
参考文献
Bulletin de la Societe Chimique de France, , vol. <4> 33, p. 1828
反应条件
bis(η3-allyl-μ-chloropalladium(II)); Rock Phos; caesium carbonate in toluene T=90°C; 21 h; Inert atmosphereMolecular sieve;
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 42 p. 9943 - 9947
反应条件
1: PTAS With tetrabutyl ammonium fluoride in tetrahydrofuran; water T=20°C; 1 h; 2: 5-chloro-2-methyl-1,3-benzoxazole With 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; bis(η3-allyl-μ-chloropalladium(II)) in tetrahydrofuran; water T=80°C; 14 h;
参考文献
Sahoo, Akhila K.; Oda, Takuro; Nakao, Yoshiaki; Hiyama, Tamejiro
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1715 - 1727
反应条件
dicyclohexyl(2',4',6'-triisopropyl-5-methoxy-3,4,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; C50H70NO4PPdS; C50H70NO4PPdS; dicyclohexyl(2',4',6'-triisopropyl-4-methoxy-3,5,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; ammonia; sodium t-butanolate in 1,4-dioxane T=80°C; 24 h; Inert atmosphere; Reagent/catalyst; Overall yield = 70 percent; Overall yield = 103.8 mg;
参考文献
Cheung, Chi Wai; Surry, David S.; Buchwald, Stephen L.
Organic Letters, 2013 , vol. 15, # 14 p. 3734 - 3737
反应条件
t-Bu Brett Phos; C44H62NO5PPdS; sodium t-butanolate in 1,4-dioxane T=80°C; 20 h; Sealed tubeInert atmosphere;
参考文献
Organic Letters, , vol. 15, # 15 p. 3998 - 4001
