1: 39 percent / Cu(OAc)2; 4 Angstroem molecular sieves; pyridine / iPr2EtN / CH2Cl2 / 24 h / 20 °C 2: 95 percent / NaBH4 / ethanol / 0.25 h / 20 °C 3: SOCl2 / CH2Cl2 / 2 h / 20 °C 4: 0.21 g / TiCl4 / CH2Cl2 / 2 h / 20 °C View Scheme
参考文献
Tan, Edwin S.; Miyakawa, Motonori; Bunzow, James R.; Grandy, David K.; Scanlan, Thomas S.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 12 p. 2787 - 2798
1: 39 percent / Cu(OAc)2; 4 Angstroem molecular sieves; pyridine / iPr2EtN / CH2Cl2 / 24 h / 20 °C 2: 95 percent / NaBH4 / ethanol / 0.25 h / 20 °C 3: SOCl2 / CH2Cl2 / 2 h / 20 °C 4: 0.21 g / TiCl4 / CH2Cl2 / 2 h / 20 °C View Scheme
参考文献
Tan, Edwin S.; Miyakawa, Motonori; Bunzow, James R.; Grandy, David K.; Scanlan, Thomas S.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 12 p. 2787 - 2798
titanium tetrachloride in dichloromethane T=20°C; 2 h;
参考文献
Tan, Edwin S.; Miyakawa, Motonori; Bunzow, James R.; Grandy, David K.; Scanlan, Thomas S.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 12 p. 2787 - 2798
1: SOCl2 / CH2Cl2 / 2 h / 20 °C 2: 0.21 g / TiCl4 / CH2Cl2 / 2 h / 20 °C View Scheme
参考文献
Tan, Edwin S.; Miyakawa, Motonori; Bunzow, James R.; Grandy, David K.; Scanlan, Thomas S.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 12 p. 2787 - 2798
1: 95 percent / NaBH4 / ethanol / 0.25 h / 20 °C 2: SOCl2 / CH2Cl2 / 2 h / 20 °C 3: 0.21 g / TiCl4 / CH2Cl2 / 2 h / 20 °C View Scheme
参考文献
Tan, Edwin S.; Miyakawa, Motonori; Bunzow, James R.; Grandy, David K.; Scanlan, Thomas S.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 12 p. 2787 - 2798
