(2S)-2-(双(叔丁氧羰基)氨基)-5-氧代戊酸甲酯合成路线 （共 10 条）
反应条件
diisobutylaluminium hydride in diethyl ether T=-78°C;
参考文献
Oelke, Alexander J.; Antonietti, Francesca; Bertone, Leonardo; Cranwell, Philippa B.; France, David J.; Goss, Rebecca J. M.; Hofmann, Tatjana; Knauer, Stephan; Moss, Steven J.; Skelton, Paul C.; Turner, Richard M.; Wuitschik, Georg; Ley, Steven V.
Chemistry - A European Journal, 2011 , vol. 17, # 15 p. 4183 - 4194
反应条件
1: Et3N; DMAP / CH2Cl2 / 20 °C 2: DIBALH / tetrahydrofuran / -78 °C View Scheme
参考文献
Burkhart, Fred; Hoffmann, Matthias; Kessler, Horst
Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 11 p. 1191 - 1192
反应条件
1: 98 percent / DMAP / acetonitrile / Ambient temperature 2: 85 percent / DIBAL / diethyl ether; hexane / 0.08 h / -78 °C View Scheme
参考文献
Wu, Wenbin; Li, Zheng; Zhou, Guangbiao; Jiang, Sheng
Tetrahedron Letters, 2011 , vol. 52, # 19 p. 2488 - 2491
反应条件
1: Et3N; DMAP / CH2Cl2 / 20 °C 2: DIBALH / tetrahydrofuran / -78 °C View Scheme
参考文献
Padron, Jose M.; Kokotos, George; Martin, Tomas; Markidis, Theodoros; Gibbons, William A.; Martin, Victor S.
Tetrahedron Asymmetry, 1998 , vol. 9, # 19 p. 3381 - 3394
反应条件
diisobutylaluminium hydride
参考文献
Burkhart, Fred; Hoffmann, Matthias; Kessler, Horst
Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 11 p. 1191 - 1192
反应条件
1: Me3SiCl 2: Et3N / methanol 3: 98 percent / DMAP / acetonitrile / Ambient temperature 4: 85 percent / DIBAL / diethyl ether; hexane / 0.08 h / -78 °C View Scheme
参考文献
Wu, Wenbin; Li, Zheng; Zhou, Guangbiao; Jiang, Sheng
Tetrahedron Letters, 2011 , vol. 52, # 19 p. 2488 - 2491
反应条件
1: 4-(N,N-dimethlyamino)pyridine; triethylamine / 1,4-dioxane; water 2: 4-(N,N-dimethlyamino)pyridine / acetonitrile 3: diisobutylaluminium hydride / diethyl ether; hexane / 0.03 h / -78 °C View Scheme
参考文献
Wu, Wenbin; Li, Zheng; Zhou, Guangbiao; Jiang, Sheng
Tetrahedron Letters, 2011 , vol. 52, # 19 p. 2488 - 2491
反应条件
1: 92 percent / N-ethylmorpholine, propylphosphonic acid anhydride 2: 100 percent / DMAP 3: 62 percent / DIBAH View Scheme
参考文献
Burkhart, Fred; Hoffmann, Matthias; Kessler, Horst
Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 11 p. 1191 - 1192
反应条件
1: 100 percent / DMAP 2: 62 percent / DIBAH View Scheme
参考文献
Burkhart, Fred; Hoffmann, Matthias; Kessler, Horst
Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 11 p. 1191 - 1192
反应条件
1: With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate in N,N-dimethyl-formamide T=85°C; 2: With cerium(III) chloride; sodium iodide in acetonitrile
参考文献
Jia, Yanxing; Zhu, Jieping
Journal of Organic Chemistry, 2006 , vol. 71, # 20 p. 7826 - 7834
