5-甲酰基-2-呋喃基苯甲酸乙酯合成路线 (共 7 条)
反应条件
1: 5-iodofuran-2-carboxaldehyde With indium; α-octadecene; lithium chloride in tetrahydrofuran T=30°C; 0.333333 h; 2: 4-iodobenzoic acid ethyl ester With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=25°C; 1.5 h; Inert atmosphere;
参考文献
Chen, Yi-Hung; Knochel, Paul
Angewandte Chemie - International Edition, 2008 , vol. 47, # 40 p. 7648 - 7651
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere;
参考文献
Kim, Seung-Hoi; Rieke, Reuben D.
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1984 - 1993
反应条件
copper(l) chloride in water T=20°C; Meerwein arylation; 48 h;
参考文献
Paizs, Csaba; Taehtinen, Petri; Lundell, Katri; Poppe, Laszlo; Irimie, Florin-Dan; Kanerva, Liisa T.
Tetrahedron Asymmetry, 2003 , vol. 14, # 13 p. 1895 - 1904
反应条件
potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in tetrahydrofuran; water T=120°C; Suzuki coupling; 0.0833333 h; microwave irradiation;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 14 p. 3880 - 3885
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethanol; toluene T=100°C; Suzuki coupling; 4 h; Inert atmosphere;
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 36 p. 7402 - 7417
反应条件
bis-triphenylphosphine-palladium(II) chloride; potassium fluoride; Ag(1+)*CH2O*NO2(1-) in dimethyl sulfoxide T=100°C; 6 h; Inert atmosphere;
参考文献
Matsuda, Shigeru; Takahashi, Masabumi; Monguchi, Daiki; Mori, Atsunori
Synlett, 2009 , # 12 p. 1941 - 1944
反应条件
hydrogenchloride; sodium nitrite 1.) water, 0.5 h, 0 to 5 deg C; 2.) acetone, 0 deg C; Multistep reaction;
参考文献
Arzneimittel-Forschung/Drug Research, , vol. 33, # 10 p. 1411 - 1416