三乙二醇二(对甲苯磺酸酯)合成路线 （共 90 条）
反应条件
1: 52 percent / KOH / dioxane / 18 h / 80 °C 2: hydrogen, p-toluenesulphonic acid / Pd/C / 25 °C / 7500.6 Torr View Scheme
参考文献
Belohradsky, Martin; Stibor, Ivan; Holy, Petr; Zavada, Jiri
Collection of Czechoslovak Chemical Communications, 1987 , vol. 52, # 10 p. 2500 - 2507
反应条件
1: 1.) t-BuOLi, 2.) LiBr*H2O / 1.) xylene, t-BuOH, 2.) xylene, t-BuOH, 85-95 deg C, 2 d 2: 81 percent / hydrogen, p-toluenesulfonic acid / 5percent Pd/C / dioxane / 5 h / 50 °C View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 55, # 7 p. 2005 - 2009
反应条件
1: NaH / tetrahydrofuran / 24 h 2: 97 percent / H2 / Pd/C / CH2Cl2 / 48 h / 20 °C / 38000 Torr View Scheme
参考文献
Keegstra, Erik M. D.; Zwikker, Jan W.; Roest, Martin R.; Jenneskens, Leonardus W.
Journal of Organic Chemistry, 1992 , vol. 57, # 24 p. 6678 - 6680
反应条件
sodium t-butanolate in 1,4-dioxane; tert-butyl alcohol T=40°C; 2 h;
参考文献
Maeda, Hirokazu; Furuyoshi, Shigeo; Nakatsuji, Yohji; Okahara, Mitsuo
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 1 p. 212 - 218
反应条件
1: 46 percent / NaH / tetrahydrofuran 2: 98 percent / H2, trace HCl / Pd-C View Scheme
参考文献
Johnson,M.R. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 357 - 371
反应条件
1: 1) NaH / 1) THF, 24 h, 2) 96 h 2: 96 percent / H2 / 10percent Pd/C / CH2Cl2 / 96 h / 25 °C / 3040 Torr View Scheme
参考文献
Keegstra, Erik M. D.; Zwikker, Jan W.; Roest, Martin R.; Jenneskens, Leonardus W.
Journal of Organic Chemistry, 1992 , vol. 57, # 24 p. 6678 - 6680
反应条件
sodium hydroxide; tetra-(n-butyl)ammonium iodide in toluene 16 h; Heating;
参考文献
Bogaschenko, Tatyana; Basok, Stepan; Kulygina, Catherine; Lyapunov, Alexander; Lukyanenko, Nikolay
Synthesis, 2002 , # 15 p. 2266 - 2270
反应条件
ammonium chloride in dimethyl sulfoxide T=85°C; 5 h;
参考文献
Holmes, Brian T.; Snow, Arthur W.
Patent: US2009/187037 A1, 2009 ;
Location in patent: Page/Page column 2-3 ;
反应条件
1: 80 percent / NaN3 / aq. ethanol / 1.)60 deg C, 1 h 2.)reflux, 8-10 h 2: 82 percent / lithium aluminum hydride / tetrahydrofuran / 10 h / Heating 3: 60 percent / toluene / 1.)0 deg C, 7 h 2.)overnight View Scheme
参考文献
Gansow, Otto A.; Kausar, A. Rashid; Triplett, Kelly B.
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 297 - 302
反应条件
NH4Br in N,N-dimethyl-formamide T=85°C; 5 h; Product distribution; Further Variations:Solvents;
参考文献
Holmes, Brian T.; Snow, Arthur W.
Patent: US2009/187037 A1, 2009 ;
Location in patent: Page/Page column 2-3 ;
