三乙二醇二(对甲苯磺酸酯)合成路线 （共 90 条）
反应条件
sodium carbonate in acetonitrile 168 h; Heating;
参考文献
Krakowiak; Bradshaw
Tetrahedron Letters, 1993 , vol. 34, # 5 p. 777 - 778
反应条件
1: With thiourea in ethanol 2: With sodium hydroxide Heating;
参考文献
Synthesis, , # 4 p. 509 - 512
反应条件
tert-butyl alcohol 1.) 80 deg C, 1 h, 2.) reflux, 10 h; Yield given. Multistep reaction;
参考文献
Luk'yanenko, N. G.; Mel'nik, O. T.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 10.2 p. 1975 - 1983
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 10 p. 2186 - 2195
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
1 h; RefluxInert atmosphere;
参考文献
SIEMENS MEDICAL SOLUTIONS USA, INC.
Patent: WO2009/102498 A1, 2009 ;
Location in patent: Page/Page column 96-97 ;
反应条件
sodium hydride in 1,4-dioxane
1.) 70 deg C, 1 h 2.) 80 deg C, 12 h;
参考文献
Luk'yanenko, N. G.; Mel'nik, O. T.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 9 p. 934 - 939
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , # 9 p. 1173 - 1178
反应条件
1: p-tert-butyl calix[4]arene With sodium hydride in tetrahydrofuran; toluene; mineral oil
0.5 h; Reflux;
2: triethylene glycol di-p-tosylate in tetrahydrofuran; toluene; mineral oil
12 h; Reflux;
参考文献
Chawla, Har Mohindra; Hundal, Geeta; Kumar; Singh, Parminder
Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2012 , vol. 72, # 3-4 p. 323 - 330
反应条件
potassium carbonate in acetonitrile
12 h;
参考文献
Alekseeva, Elena A.; Basok, Stepan S.; Mazepa, Alexander V.; Gren, Andrei I.
Mendeleev Communications, 2007 , vol. 17, # 6 p. 330 - 331
反应条件
sodium hydroxide in tetrahydrofuran
T=66°C; 24 h;
参考文献
Ouchi, Mikio; Inoue, Yoshihisa; Kanzaki, Takashi; Hakushi, Tadao
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 3 p. 887 - 888
反应条件
1: NaH / tetrahydrofuran / 24 h
2: 97 percent / H2 / Pd/C / CH2Cl2 / 48 h / 20 °C / 38000 Torr
3: 99 percent / Et3N; KOH / tetrahydrofuran; H2O / 7 h
View Scheme
参考文献
Chen, Yiyan; Baker, Gregory L.
Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6870 - 6873
反应条件
sodium carbonate in acetonitrile
24 h; Heating;
参考文献
Suzuki, Ryoko; Matsumoto, Takashi; Tanaka, Katsumi; Takeuchi, Yoshito; Taketomi, Tamotsu
Journal of Organometallic Chemistry, 2001 , vol. 636, # 1-2 p. 108 - 123
