1: With sodium t-butanolate; bis(dibenzylideneacetone)-palladium(0); N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-dimethylamine in toluene T=120°C; 15 h; 2: With hydrogenchloride; water pH=1.5; Product distribution / selectivity;
1: With pyridine; copper diacetate in dichloromethane T=20°C; 48 h; 4 Å molecular sievesUnder air; 2: With sodium hydroxide; water T=70°C; 4 h; 3: With hydrogenchloride in water pH=1.5; Product distribution / selectivity;