(2S)-N-[(4S)-5-{[(2,6-二甲基苯氧基)乙酰基]氨基}-4-羟基-1,6-二苯基-2-己烷基]-2-(2,4-二氧代四氢-1(2H)-嘧啶基)-3-甲基丁烷酰胺合成路线 （共 6 条）
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride
参考文献
Sham, Hing L; Betebenner, David A; Herrin, Thomas; Kumar, Gondi; Saldivar, Ayda; Vasavanonda, Sudthida; Molla, Akhter; Kempf, Dale J; Plattner, Jacob J; Norbeck, Daniel W
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 11 p. 1351 - 1353
反应条件
1: 94 percent / methanol 2: aq. LiOH 3: pyridine 4: conc. NH4OH 5: 61 percent / tetrahydrofuran / Heating 6: 95 percent / CF3CO2H 7: 82 percent / EDAC; HOBt View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 11 p. 1351 - 1353
反应条件
1: EDAC; HOBt 2: H2 / Pd(OH)2 3: 82 percent / EDAC; HOBt View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 11 p. 1351 - 1353
反应条件
1: aq. LiOH 2: pyridine 3: conc. NH4OH 4: 61 percent / tetrahydrofuran / Heating 5: 95 percent / CF3CO2H 6: 82 percent / EDAC; HOBt View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 11 p. 1351 - 1353
反应条件
1: 61 percent / tetrahydrofuran / Heating 2: 95 percent / CF3CO2H 3: 82 percent / EDAC; HOBt View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 11 p. 1351 - 1353
反应条件
1: 95 percent / CF3CO2H 2: 82 percent / EDAC; HOBt View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 11 p. 1351 - 1353
