3-羟基-4'-甲基黄酮合成路线 （共 12 条）
反应条件
dihydrogen peroxide; sodium hydroxide in methanol; water T=20°C;
参考文献
Dias, Tatiana A.; Duarte, Cecilia L.; Lima, Cristovao F.; Proenca, M. Fernanda; Pereira-Wilson, Cristina
European Journal of Medicinal Chemistry, 2013 , vol. 65, p. 500 - 510
反应条件
toluene-4-sulfonic acid in dichloromethane T=0°C; 3 h; other condition: chloroform-d, room temperature, 4 d;
参考文献
Adam, Waldemar; Golsch, Dieter; Hadjiarapoglou, Lazaros
Journal of Organic Chemistry, 1991 , vol. 56, # 26 p. 7292 - 7297
反应条件
in hydrogenchloride; methanol Irradiation;
参考文献
Rao, Sudhakar T.; Singh, Anil Kumar; Trivedi, Girish Kumar
Heterocycles, 1984 , vol. 22, # 6 p. 1377 - 1382
反应条件
hydrogenchloride in acetone 3 h; Ambient temperature;
参考文献
Prakash, Om; Pahuja, Saroj; Tanwar, Madan P
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994 , vol. 33, p. 272 - 273
反应条件
1: With potassium hydroxide; [bis(acetoxy)iodo]benzene in methanol Oxidation; 2: With hydrogenchloride in acetone Hydrolysis;
参考文献
Adam, Waldemar; Golsch, Dieter; Hadjiarapoglou, Lazaros
Journal of Organic Chemistry, 1991 , vol. 56, # 26 p. 7292 - 7297
反应条件
1: sodium hydroxide / ethanol / 18 h / 20 °C 2: dihydrogen peroxide; sodium hydroxide / ethanol / 18 h / 4 - 20 °C View Scheme
参考文献
Schwarz, Martina B.; Kurzwernhart, Andrea; Roller, Alexander; Kandioller, Wolfgang; Keppler, Bernhard K.; Hartinger, Christian G.
Zeitschrift fur Anorganische und Allgemeine Chemie, 2013 , vol. 639, # 8-9 p. 1648 - 1654
反应条件
1: sulfuric acid, glacial acetic acid 2: 100 percent / dimethyldioxirane / acetone; CH2Cl2 / 23 h / 0 °C 3: 100 percent / p-toluenesulfonic acid / CH2Cl2 / 3 h / 0 °C / other condition: chloroform-d, room temperature, 4 d View Scheme
参考文献
Adam, Waldemar; Golsch, Dieter; Hadjiarapoglou, Lazaros
Journal of Organic Chemistry, 1991 , vol. 56, # 26 p. 7292 - 7297
反应条件
1.1: KOH / pyridine 2.1: AcOH; H2SO4 3.1: PhI(OAc)2; KOH / methanol 3.2: HCl / acetone View Scheme
参考文献
Kline; Fromhold; McKennon; Cai; Treiberg; Ihle; Sherman; Schwan; Hickey; Warrener; Witte; Brody; Goltry; Barker; Anderson; Tanaka; Shawar; Nguyen; Langhorne; Bigelow; Embuscado; Naeemi
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 1 p. 73 - 93
反应条件
1.1: pyridine 2.1: KOH / pyridine 3.1: AcOH; H2SO4 4.1: PhI(OAc)2; KOH / methanol 4.2: HCl / acetone View Scheme
参考文献
Kline; Fromhold; McKennon; Cai; Treiberg; Ihle; Sherman; Schwan; Hickey; Warrener; Witte; Brody; Goltry; Barker; Anderson; Tanaka; Shawar; Nguyen; Langhorne; Bigelow; Embuscado; Naeemi
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 1 p. 73 - 93
反应条件
1.1: pyridine 2.1: KOH / pyridine 3.1: AcOH; H2SO4 4.1: PhI(OAc)2; KOH / methanol 4.2: HCl / acetone View Scheme
参考文献
Kline; Fromhold; McKennon; Cai; Treiberg; Ihle; Sherman; Schwan; Hickey; Warrener; Witte; Brody; Goltry; Barker; Anderson; Tanaka; Shawar; Nguyen; Langhorne; Bigelow; Embuscado; Naeemi
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 1 p. 73 - 93
