4-(1H-苯并[d]咪唑-2-基)-2-丁酮合成路线 (共 2 条)
反应条件
hydrogenchloride in water 18 h; Heating / reflux;
参考文献
PFIZER LIMITED
Patent: US2008/103130 A1, 2008 ;
Location in patent: Page/Page column 50 ;
US 20080103130 A1
反应条件
N-benzyl-N,N,N-triethylammonium chloride; sodium carbonate in 1,4-dioxane; water Alkylation; condensation; fission; Title compound not separated from byproducts;
参考文献
Popov
Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 8 p. 918 - 922