potassium carbonate in N,N-dimethyl-formamide 22 h; Ambient temperature;

potassium carbonate in acetonitrile

1.1: triethylamine / dichloromethane / 2 h / 20 °C / Inert atmosphere 2.1: diisobutylaluminium hydride / tetrahydrofuran; toluene / 2 h / 20 °C / Inert atmosphere 3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 20 °C / Inert atmosphere 4.1: trifluoroacetic acid / dichloromethane / 20 °C / Inert atmosphere 4.2: Saturated solution View Scheme

sodium hydride in N,N-dimethyl-formamide T=20°C; 24 h;

1.1: diisobutylaluminium hydride / tetrahydrofuran; toluene / 2 h / 20 °C / Inert atmosphere 2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 20 °C / Inert atmosphere 3.1: trifluoroacetic acid / dichloromethane / 20 °C / Inert atmosphere 3.2: Saturated solution View Scheme

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 20 °C / Inert atmosphere 2.1: trifluoroacetic acid / dichloromethane / 20 °C / Inert atmosphere 2.2: Saturated solution View Scheme

triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran 16 h; Ambient temperature;

triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran 10 h; Ambient temperature;

1.1: borane-THF / tetrahydrofuran / 0.5 h / -78 - 0 °C / Inert atmosphere 2.1: lithium hexamethyldisilazane / tetrahydrofuran; N,N-dimethyl-formamide / 0.02 h / -78 °C / Inert atmosphere 2.2: 0.33 h / -78 - 20 °C / Inert atmosphere 3.1: trifluoroacetic acid / dichloromethane / 1.5 h / 20 °C / Inert atmosphere 4.1: manganese(IV) oxide / dichloromethane / 1 h / 20 °C / Inert atmosphere View Scheme

1.1: lithium hexamethyldisilazane / tetrahydrofuran; N,N-dimethyl-formamide / 0.02 h / -78 °C / Inert atmosphere 1.2: 0.33 h / -78 - 20 °C / Inert atmosphere 2.1: trifluoroacetic acid / dichloromethane / 1.5 h / 20 °C / Inert atmosphere 3.1: manganese(IV) oxide / dichloromethane / 1 h / 20 °C / Inert atmosphere View Scheme