3-(4-甲氧基苯基)丙酸合成路线 （共 94 条）
反应条件
1: polyphosphoric acid 2: EtONO, HCl / ethanol; tetrahydrofuran 3: PCl5 / CCl4 View Scheme
参考文献
Simchen,G.; Kraemer,W.
Chemische Berichte, 1969 , vol. 102, p. 3656 - 3665
反应条件
1: diisobutylaluminium hydride / toluene / 2 h / -78 °C / Inert atmosphere 2: tetra-n-butylammonium tribromide / acetonitrile / 0.5 h / 20 °C 3: ethanol / 1 h / Reflux View Scheme
参考文献
DEVELOPMENT CENTER FOR BIOTECHNOLOGY
Patent: US2012/172374 A1, 2012 ;
反应条件
methylphenylsilane; trimethylacetic anhydride; tris(4-methylphenyl)-phosphine; bis(dibenzylideneacetone)-palladium(0) in toluene T=60°C; 20 h; Schlenk techniqueInert atmosphere;
参考文献
Fujihara, Tetsuaki; Cong, Cong; Terao, Jun; Tsuji, Yasushi
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 17 p. 3420 - 3424
反应条件
1: polyphosphoric acid 2: EtONO, HCl / ethanol; tetrahydrofuran View Scheme
参考文献
Simchen,G.; Kraemer,W.
Chemische Berichte, 1969 , vol. 102, p. 3656 - 3665
反应条件
diphenyl phosphoryl azide; triethylamine in toluene T=20 - 80°C; 1.25 h; Inert atmosphere;
参考文献
Nishimura, Takuya; Yamada, Kouhei; Takebe, Tohru; Yokoshima, Satoshi; Fukuyama, Tohru
Organic Letters, 2014 , vol. 16, # 4 p. 1268 - 1268
反应条件
sodium azide; chloroform; sulfuric acid
参考文献
Barger; Walpole
Journal of the Chemical Society, 1909 , vol. 95, p. 1722
反应条件
1: 48percent aq. HBr 2: H2SO4 View Scheme
参考文献
Kuchar, Miroslav; Brunova, Bohumila; Rejholec, Vaclav; Roubal, Zdenek; Nemecek, Oldrich
Collection of Czechoslovak Chemical Communications, 1981 , vol. 46, # 5 p. 1173 - 1187
反应条件
lithium aluminium tetrahydride in diethyl ether 1.) 0 deg C, 0.5 h, 2.) 25 deg C, 5 h;
参考文献
Semmelhack, M.F.; Helquist, Paul; Jones, L.D.; Keller, Leonard; Mendelson L.; et al.
Journal of the American Chemical Society, 1981 , vol. 103, # 21 p. 6460 - 6471
反应条件
1: 1.) SOCl2, 2.) AlCl3 / 2.) CH2Cl2 2: 79 percent / aluminium bromide / benzene / 4.5 h / Heating View Scheme
参考文献
Monobe; Chen; Zhao; Hu; Miyake; Fujii; Ozaki; Shimizu
Molecular Crystals and Liquid Crystals, 2011 , vol. 545, p. 149 - 155
反应条件
PPA T=120°C; 0.0833333 h;
参考文献
Heffner; Joullie
Synthetic Communications, 1991 , vol. 21, # 21 p. 2231 - 2256
