3-(4-甲氧基苯基)丙酸合成路线 （共 94 条）
反应条件
anhydrous tetramethylammonium chloride; sodium hydride 1.) hexane, 25 deg C, 30 min; 50 deg C, 2 h, 2.) methyl ethyl ketone, 50 - 60 deg C, 30 min, 3.) RT, 6 h;
参考文献
Fatope, Majekodunmi O.; Adeniyl, Adebayo E.
Synthetic Communications, 1985 , vol. 15, # 4 p. 307 - 310
反应条件
anhydrous ammonium carbonate; diphosphorous tetraiodide in carbon disulfide T=20°C; 7 h;
参考文献
Telvekar, Vikas N.; Rane, Rajesh A.
Tetrahedron Letters, 2007 , vol. 48, # 34 p. 6051 - 6053
参考文献
Goldschmiedt; v. Fraenkel
Monatshefte fuer Chemie, 1914 , vol. 35, p. 386
反应条件
1: 97 percent / H2SO4 / 20 °C 2: 88 percent / hydrazine hydrate / methanol / 20 °C View Scheme
参考文献
Hanif, Muhammad; Khan, Imtiaz; Rama, Nasim Hasan; Noreen, Shagufta; Choudhary, Muhammad Iqbal; Jones, Peter G.; Iqbal, Mazhar
Medicinal Chemistry Research, 2012 , vol. 21, # 11 p. 3885 - 3896
反应条件
dipotassium peroxodisulfate in water T=25°C; pH=1.7; 0.025 h; UV-irradiation;
参考文献
Bietti, Massimo; Capone, Alberto
Journal of Organic Chemistry, 2006 , vol. 71, # 14 p. 5260 - 5267
反应条件
1: potassium peroxydisulfate / H2O / 0.03 h / 25 °C / pH 1.7 / UV-irradiation 2: potassium peroxydisulfate / H2O / 0.01 h / 25 °C / pH 1.7 / UV-irradiation View Scheme
参考文献
Bietti, Massimo; Capone, Alberto
Journal of Organic Chemistry, 2006 , vol. 71, # 14 p. 5260 - 5267
反应条件
Iron(II,III) oxide nanopowder
T=280°C; dowtherm AInert atmosphere;
参考文献
Goossen, Lukas J.; Mamone, Patrizia; Oppel, Christoph
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 1 p. 57 - 63
反应条件
1: 1.) SOCl2, 2.) AlCl3 / 2.) CH2Cl2
2: 79 percent / aluminium bromide / benzene / 4.5 h / Heating
3: 74 percent / sodium methoxide / methanol / 50 h / Heating
4: sodium borohydride / methanol / 0.33 h / Ambient temperature
5: toluene-p-sulphonic acid / benzene / 1.5 h / Heating
6: 80 percent / sodium carbonate, water / dioxane / 5.5 h / Heating
View Scheme
参考文献
Phialas, Memnon; Sammes, Peter G.; Kennewell, Peter D.; Westwood, Robert
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 4 p. 687 - 695
反应条件
1: 1.) thionylchloride / 1.) 85 deg C, 40 min, 2.) 95 deg C, 25 min, 140 deg C
2: KOH / pyridine / 0.25 h
3: c.c.H2SO4 / acetic acid
View Scheme
参考文献
Hashimoto, Keiji; Nakahara, Sachiko; Inoue, Takehisa; Sumida, Yoshio; Takahashi, Mutsuko; Masada, Yoshiro
Chemical & Pharmaceutical Bulletin, 1985 , vol. 33, # 11 p. 5088 - 5091
反应条件
boron trifluoride diethyl etherate
T=80 - 90°C; 1.5 h;
参考文献
Siddaiah, Vidavalur; Rao, Chunduri Venkata; Venkateswarlu, Somepalli; Subbaraju, Gottumukkala V.
Tetrahedron, 2006 , vol. 62, # 5 p. 841 - 846
