1: With methanol; (1R,2S)-N-pyrrolidinyl norephedrine; dimethyl zinc in toluene T=20°C; 9 h; 2: With citric acid in water; toluene Product distribution / selectivity;
参考文献
MERCK and CO., INC.
Patent: EP1017666 B1, 2003 ;
Location in patent: Page/Page column 6; 12 ;