3-羟基-2,2-二甲基丙腈合成路线 （共 16 条）
反应条件
1: With sodium tetrahydroborate in tetrahydrofuran; water T=20°C; 3 h; 2: With hydrogenchloride; water in tetrahydrofuran
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP1847531 A1, 2007 ;
Location in patent: Page/Page column 51 ;
EP 1847531 A1
反应条件
ammonia; sodium methylate; potassium iodide in methanol T=5°C; electrooxidation;
参考文献
Okimoto, Mitsuhiro; Chiba, Toshiro
Journal of Organic Chemistry, 1988 , vol. 53, # 1 p. 218 - 219
反应条件
hydrogenchloride; sodium borohydride; triethylamine in tetrahydrofuran; water
参考文献
US5859014 A1, ;
US 5859014 A
反应条件
tetracarbonylbis(μ-chloro)dirhodium(I); carbon monoxide; hydrogen; triethylamine in toluene T=130°C; P=121600 Torr; 63 h; Yield given. Yields of byproduct given;
参考文献
Journal of Organometallic Chemistry, , vol. 396, # 2/3 p. 375 - 383
反应条件
tetracarbonylbis(μ-chloro)dirhodium(I); hydrogen; triethylamine in toluene T=130°C; P=121600 Torr; 63 h; Yield given. Yields of byproduct given;
参考文献
Journal of Organometallic Chemistry, , vol. 396, # 2/3 p. 375 - 383
参考文献
Monatshefte fuer Chemie, , vol. 27, p. 955
反应条件
sodium hydroxide in ethanol
参考文献
Bulletin de la Societe Chimique de France, , p. 4379 - 4383
反应条件
(i) LiNEt2, HMPT, benzene, (ii) /BRN= 1209228/; Multistep reaction;
参考文献
Journal of Organometallic Chemistry, , vol. 57, p. C36 - C38
反应条件
in methanol; water Heating;
参考文献
Helvetica Chimica Acta, , vol. 45, p. 1071 - 1075
反应条件
durch einer Wasserstoff-Sauerstoff-Flamme;
