7-苄氧基-3,4-二氢喹唑啉-4-酮合成路线 （共 4 条）
反应条件
sodium hydride in N,N-dimethyl-formamide T=140°C; 4 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2008/20302 A2, 2008 ;
Location in patent: Page/Page column 40-41 ;
WO 2008/020302 A2
反应条件
sodium in benzyl alcohol T=120°C; 18 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/94410 A1, 2004 ;
Location in patent: Page 124 ;
WO 2004/094410 A1
反应条件
1: benzyl alcohol With sodium hydride in N,N-dimethyl-formamide T=0 - 20°C; 0.5 h; 2: 7-fluoro-3,4-dihydroquinazolin-4-one in N,N-dimethyl-formamide T=0 - 95°C; 16 h; Product distribution / selectivity;
参考文献
Pfizer Inc
Patent: US2007/299076 A1, 2007 ;
Location in patent: Page/Page column 39; 40-41 ;
反应条件
hydrogenchloride in water; N,N-dimethyl-formamide; mineral oil; Petroleum ether
参考文献
Zeneca Limited; Zeneca Pharma S.A.,
Patent: US5962458 A1, 1999 ;
US 5962458 A
