4,4-二甲基-2-苯基-2-噁唑啉合成路线 （共 73 条）
反应条件
1: 1-bromo-2-(4,4-dimethyl-3,4-dihydrooxazol-2-yl)benzene With Ph2CuLi*LiCN in diethyl ether T=0°C; 0.5 h; 2: benzyl chloride in diethyl ether T=20°C; 1 h;
参考文献
Journal of Organometallic Chemistry, , vol. 689, # 1 p. 154 - 157
反应条件
1: CH2Cl2 / 14 h / Ambient temperature 2: 70 percent / thionyl chloride / benzene; CH2Cl2 / 1.) reflux, 2.) room temperature, 2.5 h 3: 2.) ethanol / 1.) pentane, -78 deg C, 2.) pentane, room temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 110, p. 7178
反应条件
1: 70 percent / thionyl chloride / benzene; CH2Cl2 / 1.) reflux, 2.) room temperature, 2.5 h 2: 2.) ethanol / 1.) pentane, -78 deg C, 2.) pentane, room temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 110, p. 7178
反应条件
1: thionyl chloride / 1 h / 100 °C 2: CH2Cl2 / 14 h / Ambient temperature 3: 70 percent / thionyl chloride / benzene; CH2Cl2 / 1.) reflux, 2.) room temperature, 2.5 h 4: 2.) ethanol / 1.) pentane, -78 deg C, 2.) pentane, room temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 110, p. 7178
反应条件
1: 1-bromo-2-(4,4-dimethyl-3,4-dihydrooxazol-2-yl)benzene With Ph2CuLi*LiCN in diethyl ether T=0°C; 0.5 h; 2: benzyl bromide in diethyl ether T=20°C; 1 h;
参考文献
Journal of Organometallic Chemistry, , vol. 689, # 1 p. 154 - 157
反应条件
1: pyridine View Scheme
参考文献
Journal of the American Chemical Society, , vol. 77, p. 5113,5115
反应条件
N-bromosuccinmide in dichloromethane T=20°C; 0.5 h;
参考文献
Synthesis, , # 18 p. 2996 - 3002
反应条件
1: BuLi / diethyl ether / -78 °C 2: 1) trimethyltin chloride (Me3SnCl) / 2) (Ph3P)4Pd <tetrakis(triphenylphosphine)palladium(O)> / 1) in Et2O, -78 deg C, 2) C6H6, 12h, reflux View Scheme
参考文献
Tetrahedron Letters, , vol. 27, # 43 p. 5269 - 5270
反应条件
H2NC(Me)PhCH2OH in nitromethane 6 h; Heating;
参考文献
Booth, Brian L.; Jibodu, Kehinde O.; Proenca, M. Fernanda J. R. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 5 p. 1067 - 1073
反应条件
1: CHCl3 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 78, p. 907,910
