6-氯-3,4-二氢-1H-喹啉-2-酮合成路线 （共 10 条）
反应条件
aluminium trichloride T=140°C; Cyclization; 24 h;
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 20 p. 3718 - 3735
反应条件
potassium carbonate; [pentamethylcyclopentadienylRhCl2]2 in acetone T=100°C; 20 h;
参考文献
Organic Letters, , vol. 6, # 16 p. 2785 - 2788
反应条件
hydrogenchloride; sodium chlorate; acetic acid T=20°C; Chlorination; 0.333333 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 14 p. 1559 - 1562
反应条件
1: 100 percent / acetone / 1 h / Heating 2: 94 percent / AlCl3 / 24 h / 140 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 20 p. 3718 - 3735
反应条件
aluminium trichloride in 1,2-dichloro-ethane 24 h; Ambient temperature;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 19 p. 1450 - 1451
反应条件
hydrogenchloride 0.5 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 25, p. 1279 - 1281
反应条件
1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; caesium carbonate / tetrahydrofuran; water / 16 h / |Reflux 2: tri-ruthenium(0)dodecacarbonyl / chlorobenzene; N,N-dimethyl acetamide / 20 - 120 °C / |Sealed tube View Scheme
参考文献
Journal of the American Chemical Society, , vol. 136, # 3 p. 1125 - 1131
参考文献
DE415096 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 15, p. 339
Chemische Berichte, , vol. 60, p. 860
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone; trichlorophosphate in N,N-dimethyl-formamide T=20°C; Chlorination; aromatization; 6 h;
参考文献
Lee, Byoung Se; Chu, Soyoung; Lee, Byung Chul; Chi, Dae Yoon; Choe, Yearn Seong; Jeong, Kyung Ja; Jin, Changbae
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1559 - 1562
反应条件
1: POCl3; DDQ / dimethylformamide / 6 h / 20 °C
2: dimethylformamide / 80 °C
3: 4 M aq. H2SO4 / 80 °C
View Scheme
参考文献
Lee, Byoung Se; Chu, Soyoung; Lee, Byung Chul; Chi, Dae Yoon; Choe, Yearn Seong; Jeong, Kyung Ja; Jin, Changbae
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1559 - 1562
