2-叔丁基-6-(三氟甲基)嘧啶-4-醇合成路线 （共 3 条）
反应条件
1: 2,2-dimethylpropaneimidamide hydrochloride With sodium methylate in methanol; ethanol T=20°C; 0.5 h; 2: 4,4,4-trifluoro-3-oxo-butyric acid methyl ester in methanol; ethanol T=78°C; 3 h;
参考文献
MERCK and CO., INC.
Patent: WO2007/64553 A2, 2007 ;
Location in patent: Page/Page column 73 ;
WO 2007/064553 A2
反应条件
1: With sodium methylate in methanol T=80°C; 16 h; Reflux; 2: With hydrogenchloride in methanol; water
参考文献
SUMITOMO CHEMICAL COMPANY, LIMITED; MIZUNO, Hajime
Patent: WO2010/134478 A1, 2010 ;
Location in patent: Page/Page column 148; 149 ;
反应条件
sodium ethanolate in ethanol
参考文献
BASF Aktiengesellschaft
Patent: US6352981 B1, 2002 ;
Location in patent: Page column 11 ;
