2-氨基-5-甲基噻吩-3-羧酸甲酯合成路线 (共 4 条)
反应条件
sulfur; triethylamine in N,N-dimethyl-formamide
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 2 p. 305 - 308
参考文献
Horiuchi, Takao; Chiba, Jun; Uoto, Kouichi; Soga, Tsunehiko
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 2 p. 305 - 308
参考文献
Eli Lilly and Company; Eli Lilly and Company Limited
Patent: US5817656 A1, 1998 ;
US 5817656 A
Title/Abstract Full Text Show Details
Eli Lilly and Company; Lilly Industries Limited
Patent: US5605897 A1, 1997 ;
反应条件
1: With methanol; water; lithium hydroxide in tetrahydrofuran
T=85°C; 2 h;
2: With hydrogenchloride in tetrahydrofuran; water
参考文献
Roche Palo Alto LLC
Patent: US2006/40927 A1, 2006 ;
Location in patent: Page/Page column 36 ;
US 20060040927 A1