1,6,7-三甲基-1H-咪唑并[4,5-c]吡啶-2-胺合成路线 (共 7 条)
反应条件
1: 78 percent / H2SO4, HNO3 / 5 h / 100 °C 2: 94 percent / H2, gl. AcOH / 10percent Pd/C / 12 h / 60 °C / 2585.7 Torr 3: 60 percent / Na2CO3 / acetone / 3 h / Ambient temperature 4: 62 percent / lithium aluminum hydride / tetrahydrofuran / 18 h / Ambient temperature 5: 18 percent / H2SO4, fuming HNO3 / 3 h / 110 °C 6: H2 / 10percent Pd/C / ethanol / 18 h / 2585.7 Torr / Ambient temperature 7: ethanol / 18 h / 110 °C View Scheme
参考文献
Tanga; Bupp; Tochimoto
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 717 - 727
反应条件
1: 94 percent / H2, gl. AcOH / 10percent Pd/C / 12 h / 60 °C / 2585.7 Torr 2: 60 percent / Na2CO3 / acetone / 3 h / Ambient temperature 3: 62 percent / lithium aluminum hydride / tetrahydrofuran / 18 h / Ambient temperature 4: 18 percent / H2SO4, fuming HNO3 / 3 h / 110 °C 5: H2 / 10percent Pd/C / ethanol / 18 h / 2585.7 Torr / Ambient temperature 6: ethanol / 18 h / 110 °C View Scheme
参考文献
Tanga; Bupp; Tochimoto
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 717 - 727
反应条件
1: 60 percent / Na2CO3 / acetone / 3 h / Ambient temperature 2: 62 percent / lithium aluminum hydride / tetrahydrofuran / 18 h / Ambient temperature 3: 18 percent / H2SO4, fuming HNO3 / 3 h / 110 °C 4: H2 / 10percent Pd/C / ethanol / 18 h / 2585.7 Torr / Ambient temperature 5: ethanol / 18 h / 110 °C View Scheme
参考文献
Tanga; Bupp; Tochimoto
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 717 - 727
反应条件
1: 18 percent / H2SO4, fuming HNO3 / 3 h / 110 °C 2: H2 / 10percent Pd/C / ethanol / 18 h / 2585.7 Torr / Ambient temperature 3: ethanol / 18 h / 110 °C View Scheme
参考文献
Tanga; Bupp; Tochimoto
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 717 - 727
反应条件
1: 62 percent / lithium aluminum hydride / tetrahydrofuran / 18 h / Ambient temperature 2: 18 percent / H2SO4, fuming HNO3 / 3 h / 110 °C 3: H2 / 10percent Pd/C / ethanol / 18 h / 2585.7 Torr / Ambient temperature 4: ethanol / 18 h / 110 °C View Scheme
参考文献
Tanga; Bupp; Tochimoto
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 717 - 727
反应条件
1: H2 / 10percent Pd/C / ethanol / 18 h / 2585.7 Torr / Ambient temperature 2: ethanol / 18 h / 110 °C View Scheme
参考文献
Tanga; Bupp; Tochimoto
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 717 - 727
反应条件
in ethanol T=110°C; 18 h; Yield given;
参考文献
Tanga; Bupp; Tochimoto
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 717 - 727