顺式-11-十八烯酸甲酯合成路线 （共 28 条）
反应条件
1: 7.5 g / pyridinium chlorochromate / CH2Cl2 / 1 h / Ambient temperature 2: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: 1.) B2H6, 2.) H2O2/3N NaOH / 1.) diglyme, 5h, 2.) room temperature, overnight 2: H2/RaNi / ethyl acetate / 4 h / 80 °C / 76000.1 Torr 3: 85 percent / PBr3 / benzene / 5 h / Ambient temperature 4: 22 g / acetonitrile / 8 h / Heating 5: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: 1.) H2/Ni, 2.) LiAlH4 / 2.) ether 2: 7.5 g / pyridinium chlorochromate / CH2Cl2 / 1 h / Ambient temperature 3: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: H2/RaNi / ethyl acetate / 4 h / 80 °C / 76000.1 Torr 2: 85 percent / PBr3 / benzene / 5 h / Ambient temperature 3: 22 g / acetonitrile / 8 h / Heating 4: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: (i) NaI, (ii) /BRN= 610776/ 2: NaOEt / dimethylformamide 3: aq. NaOH / methanol 4: diethyl ether View Scheme
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 1984 - 1997
反应条件
1: aq. NaOH / methanol 2: diethyl ether View Scheme
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 1984 - 1997
反应条件
1.1: toluene-4-sulfonic acid / dichloromethane / 20 °C 2.1: n-butyllithium / tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide; hexane / 0.5 h / -60 °C 2.2: -20 - 20 °C 3.1: Jone's reagent / acetone / 0 - 4 °C 4.1: sulfuric acid / 20 °C 5.1: hydrogen; ethylenediamine / ethanol; water View Scheme
参考文献
Synlett, , # 6 p. 809 - 812
反应条件
1: sulfuric acid / 20 °C 2: hydrogen; ethylenediamine / ethanol; water View Scheme
参考文献
Synlett, , # 6 p. 809 - 812
反应条件
1.1: n-butyllithium / tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide; hexane / 0.5 h / -60 °C 1.2: -20 - 20 °C 2.1: Jone's reagent / acetone / 0 - 4 °C 3.1: sulfuric acid / 20 °C 4.1: hydrogen; ethylenediamine / ethanol; water View Scheme
参考文献
Synlett, , # 6 p. 809 - 812
反应条件
1: Jone's reagent / acetone / 0 - 4 °C 2: sulfuric acid / 20 °C 3: hydrogen; ethylenediamine / ethanol; water View Scheme
参考文献
Synlett, , # 6 p. 809 - 812
