芴甲氧羰基-L-β-高亮氨酸合成路线 （共 7 条）
反应条件
silver trifluoroacetate; silica gel in ethyl acetate T=50°C; Wolff rearrangement; 0.25 h;
参考文献
Koch, Karen; Podlech, Joachim
Synthetic Communications, 2005 , vol. 35, # 21 p. 2789 - 2794
反应条件
1: N-Fmoc-L-leucine With TEA; isobutyl chloroformate in tetrahydrofuran; diethyl ether T=0°C; 2: diazomethane in diethyl ether 3: With silver trifluoroacetate; sodium carbonate; sodium thiosulfate in 1,4-dioxane Further stages.;
参考文献
Coffey; Drauz; Roberts; Skidmore; Smith
Chemical communications (Cambridge, England), 2001 , # 22 p. 2330 - 2331
反应条件
1: 1.) i-BuOCOCl, NMM / 1.) THF, -20 deg C, 20 min, 2.) THF, Et2O, -5 deg C, 4 h 2: 66 percent / CF3COOAg, Et3N / tetrahydrofuran; H2O View Scheme
参考文献
Helvetica Chimica Acta, , vol. 81, # 2 p. 187 - 206
反应条件
1: tetrahydrofuran; diethyl ether / 3 h / Ambient temperature 2: silver benzoate, H2O / dioxane / Ambient temperature View Scheme
参考文献
Synthesis, , # 6 p. 837 - 841
反应条件
1: 96 percent / CH2Cl2 / 1 h / Ambient temperature 2: 82 percent / silver benzoate / dioxane; H2O / 70 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 13 p. 1969 - 1971
反应条件
dimethyl sulfoxide T=120°C; 0.25 h; Microwave irradiation;
参考文献
Chimia, , vol. 64, # 3 p. 200 - 202
反应条件
dimethyl sulfoxide
T=120°C; 0.25 h; Microwave irradiation;
参考文献
Hoeck, Stefan; Marti, Roger; Riedl, Rainer; Simeunovic, Marina
Chimia, 2010 , vol. 64, # 3 p. 200 - 202
