6-氯-9-(2-O-甲基-beta-D-呋喃核糖基)-9H-嘌呤-2-胺合成路线 (共 3 条)
反应条件
1: 4-dimethylaminopyridine; Et3N / acetonitrile / 0.67 h / 20 °C 2: 1.1 g / isoamylnitrile / tetrahydrofuran / 2 h / Heating 3: 80 percent / methanolic ammonia / 4 h / 125 °C View Scheme
参考文献
Tetrahedron, , vol. 56, # 8 p. 1047 - 1056
反应条件
1,4-diaza-bicyclo[2.2.2]octane in water T=90°C; Oxidation; 0.75 h;
参考文献
Beigelman, Leonid; Haeberli, Peter; Sweedler, David; Karpeisky, Alexander
Tetrahedron, 2000 , vol. 56, # 8 p. 1047 - 1056
参考文献
Ribozyme Pharmaceuticals, Inc.
Patent: US5962675 A1, 1999 ;