2-氨基-4-(三氟甲基)-苯硫醇合成路线 （共 14 条）
反应条件
sodium hydroxide in ethylene glycol T=125°C; 3 h;
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 9 p. 3141 - 3152
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Journal of medicinal chemistry, , vol. 14, # 3 p. 248 - 251
反应条件
hydrogen; palladium on activated charcoal in tetrahydrofuran
参考文献
Medicinal Chemistry Research, , vol. 10, # 1 p. 19 - 29
反应条件
1: pyridine / 2 h / 120 °C 2: phosphorus pentasulfide / benzene / 3 h / Heating 3: NaH / toluene / 0.5 h / Heating 4: aq. NaOH / ethane-1,2-diol / 3 h / 125 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 9 p. 3141 - 3152
反应条件
1: phosphorus pentasulfide / benzene / 3 h / Heating 2: NaH / toluene / 0.5 h / Heating 3: aq. NaOH / ethane-1,2-diol / 3 h / 125 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 9 p. 3141 - 3152
反应条件
triethylamine in diethyl ether 0.166667 h; Inert atmosphereGloveboxSonication;
参考文献
Inorganic Chemistry, , vol. 52, # 5 p. 2323 - 2334
反应条件
1: 100 percent / KOH / propan-2-ol 2: dithiothreitol / dimethylformamide View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 6 p. 1532 - 1536
反应条件
hydrogenchloride; iron
参考文献
Journal of medicinal chemistry, , vol. 15, # 5 p. 523 - 529
反应条件
(i) Na2S, sulfur, (ii) Sn, aq. HCl; Multistep reaction;
参考文献
Canadian Journal of Chemistry, , vol. 43, p. 2610 - 2612
反应条件
copper(l) iodide; potassium carbonate in dimethyl sulfoxide T=120°C; 48 h; Inert atmosphere; regioselective reaction;
参考文献
Dai, Chuan; Sun, Xiaofei; Tu, Xingzhao; Wu, Li; Zhan, Dan; Zeng, Qingle
Chemical Communications, 2012 , vol. 48, # 43 p. 5367 - 5369
