air; (R,R)-Ph-BOX; copper-exchanged zeolite Y in acetonitrile
T=25°C; 16 h; Title compound not separated from byproducts;
参考文献
Taylor, Sophia; Gullick, John; McMorn, Paul; Bethell, Donald; Page, Philip C. Bulman; Hancock, Frederick E.; King, Frank; Hutchings, Graham J.
Journal of the Chemical Society. Perkin Transactions 2, 2001 , # 9 p. 1714 - 1723
1: 80.6 percent / potassium hydroxide / methanol / 0 - 20 °C
2: 2,2-bis[(4R)-4,5-dihydro-4-phenyl-1,3-oxazol-2-yl]propane; air / copper-exchanged zeolite Y / acetonitrile / 16 h / 25 °C
View Scheme
参考文献
Taylor, Sophia; Gullick, John; McMorn, Paul; Bethell, Donald; Page, Philip C. Bulman; Hancock, Frederick E.; King, Frank; Hutchings, Graham J.
Journal of the Chemical Society. Perkin Transactions 2, 2001 , # 9 p. 1714 - 1723
copper(II) bis(trifluoromethanesulfonate); (-)-2,2′-isopropylidenebis[(4S)-4-phenyl-2-oxazoline] in acetonitrile
T=20°C; 12 h; optical yield given as percent eeenantioselective reaction;
参考文献
Jeffs, Laura; Arquier, Damien; Kariuki, Benson; Bethell, Donald; Page, Philip C. Bulman; Hutchings, Graham J.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 4 p. 1079 - 1084
pyridine in dichloromethane
T=0 - 23°C; Inert atmosphere;
参考文献
Craig, Robert A.; O'Connor, Nicholas R.; Goldberg, Alexander F. G.; Stoltz, Brian M.
Chemistry - A European Journal, 2014 , vol. 20, # 16 p. 4806 - 4813
