反式-N-BOC-4-氰基-L-脯氨酸甲酯合成路线 （共 6 条）
反应条件
in DMF (N,N-dimethyl-formamide) T=90°C;
参考文献
US2005/153877 A1, ;
Page/Page column 90; 124-125 ;
US 20050153877 A1
反应条件
in dimethyl sulfoxide
参考文献
Merck and Co., Inc.
Patent: US5821261 A1, 1998 ;
反应条件
1: thionyl chloride / methanol / 15 h / 0 - 20 °C 2: triethylamine / acetonitrile / 0 - 20 °C 3: triethylamine / dichloromethane / 20 h / 0 - 20 °C 4: dimethyl sulfoxide / 4 h / 80 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 36 p. 9539 - 9543
Angew. Chem., , vol. 125, # 36 p. 9718 - 9722
反应条件
1: triethylamine / acetonitrile / 0 - 20 °C 2: triethylamine / dichloromethane / 20 h / 0 - 20 °C 3: dimethyl sulfoxide / 4 h / 80 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 36 p. 9539 - 9543
Angew. Chem., , vol. 125, # 36 p. 9718 - 9722
反应条件
1: triethylamine / dichloromethane / 20 h / 0 - 20 °C 2: dimethyl sulfoxide / 4 h / 80 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 36 p. 9539 - 9543
Angew. Chem., , vol. 125, # 36 p. 9718 - 9722
反应条件
in dimethyl sulfoxide T=80°C; 4 h;
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 36 p. 9539 - 9543
Angew. Chem., , vol. 125, # 36 p. 9718 - 9722
