1: L-alpha-glycerylphosphorylcholine With di(n-butyl)tin oxide in isopropyl alcohol 1 h; Heating; 2: n-octadecanoic acid chloride With TEA in isopropyl alcohol T=20°C; 0.583333 h; Further stages.;

Tris-HCl buffer; calcium chloride; phospholipase A2 in diethyl ether; ethanol T=20°C; deacylation; pH=8.0; 19 h;

hydrogen; palladium dihydroxide Yield given;

1: L-alpha-glycerylphosphorylcholine; di(n-butyl)tin oxide in methanol 1 h; Heating / reflux; 2: n-hexadecanoyl chloride With triethylamine in isopropyl alcohol

1: 1.) Et3N, 2.) H2O / 1.) CH2Cl2, 0-5 deg C, 4 h, 2.) RT, 30 min 2: 60 percent / ethanol; CHCl3 / 60 h / 60 - 70 °C 3: H2 / 10percent Pd/C / CHCl3; methanol / 4 h / Ambient temperature View Scheme

1: 84.5 percent / DMAP, DCC / CH2Cl2 / Ambient temperature 2: 54 percent / TFA, 70percent aq. HClo4 / CH2Cl2 / 0.17 h / 0 - 5 °C 3: Pb(OAc)4 / ethyl acetate / 4 h / Ambient temperature 4: 88 percent / NaBH4 / methanol / 4 h / Ambient temperature 5: 1.) Et3N, 2.) H2O / 1.) CH2Cl2, 0-5 deg C, 4 h, 2.) RT, 30 min 6: 60 percent / ethanol; CHCl3 / 60 h / 60 - 70 °C 7: H2 / 10percent Pd/C / CHCl3; methanol / 4 h / Ambient temperature View Scheme

1: 88 percent / NaBH4 / methanol / 4 h / Ambient temperature 2: 1.) Et3N, 2.) H2O / 1.) CH2Cl2, 0-5 deg C, 4 h, 2.) RT, 30 min 3: 60 percent / ethanol; CHCl3 / 60 h / 60 - 70 °C 4: H2 / 10percent Pd/C / CHCl3; methanol / 4 h / Ambient temperature View Scheme

1: 60 percent / ethanol; CHCl3 / 60 h / 60 - 70 °C 2: H2 / 10percent Pd/C / CHCl3; methanol / 4 h / Ambient temperature View Scheme

1: diisopropyl ether / 4 h / Ambient temperature; lipase Amano P from Pseudomonas fluorescens 2: POCl3 3: H2 / Pd(OH)2 View Scheme

1: POCl3 2: H2 / Pd(OH)2 View Scheme