1: KO-t-Bu / 2-methyl-propan-2-ol / 3 h / Heating 2: 6 h / Heating 3: methanol. NaOMe / 1 h / Ambient temperature View Scheme
参考文献
Chan, Wan K.; Huang, Fu-Chih; Morrissette, Matthew M.; Warus, James D.; Moriarty, Kevin J.; Galemmo, Robert A.; Dankulich, William D.; Poli, Gregory; Sutherland, Charles A.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3756 - 3768
1: sodium borohydride / ethanol / 16 h / Ambient temperature 2: pyridine, thionyl chloride / benzene / 16 h / Heating 3: H2O; ethanol / 24 h / Heating 4: concd. HCl, acetic acid / 24 h / Heating View Scheme
参考文献
Atkinson, David C.; Godfrey, Keith E.; Meek, Bernard; Saville, John F.; Stillings, Michael R.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1353 - 1360
1: sodium borohydride / ethanol / 16 h / Ambient temperature 2: pyridine, thionyl chloride / benzene / 16 h / Heating 3: H2O; ethanol / 24 h / Heating View Scheme
参考文献
Atkinson, David C.; Godfrey, Keith E.; Meek, Bernard; Saville, John F.; Stillings, Michael R.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1353 - 1360
sodium tetrahydroborate in ethanol 16 h; Ambient temperature;
参考文献
Atkinson, David C.; Godfrey, Keith E.; Meek, Bernard; Saville, John F.; Stillings, Michael R.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1353 - 1360
