(±)-α-羟基-γ-丁内酯合成路线 （共 32 条）
反应条件
hydrogen; toluene-4-sulfonic acid; Ru-carbon in water; isopropyl alcohol T=60°C; P=15001.2 Torr; 6 h;
参考文献
Kagayama, Takashi; Sakaguchi, Satoshi; Ishii, Yasutaka
Tetrahedron Letters, 2005 , vol. 46, # 21 p. 3687 - 3689
反应条件
hydrogen in water T=300°C; 5 h;
参考文献
RHODIA OPERATIONS; Jacquot, Roland; Marion, Philippe
Patent: US2013/204015 A1, 2013 ;
Location in patent: Paragraph 0253; 0254; 0255; 0256; 0257; 0258 ;
反应条件
1: With oxygen; toluene-4-sulfonic acid in isopropyl alcohol T=70°C; 6 h; 2: With hydrogen; palladium on activated charcoal in isopropyl alcohol T=60°C; P=60004.8 Torr; 6 h;
参考文献
Kagayama, Takashi; Sakaguchi, Satoshi; Ishii, Yasutaka
Tetrahedron Letters, 2005 , vol. 46, # 21 p. 3687 - 3689
参考文献
Tetrahedron Letters, , vol. 29, # 17 p. 2063 - 2066
反应条件
monobromoacetic acid; sodium bromide in water-d2 T=135°C; 3 h; Reagent/catalystTime;
参考文献
US2013/204016 A1, ;
Paragraph 0127 ;
反应条件
1: With sodium tetrahydroborate in methanol T=20°C; 1 h; 2: With hydrogenchloride in water T=20°C; 2 h;
参考文献
Kagayama, Takashi; Sakaguchi, Satoshi; Ishii, Yasutaka
Tetrahedron Letters, 2005 , vol. 46, # 21 p. 3687 - 3689
反应条件
acetic acid; zinc in tetrahydrofuran T=50°C; Inert atmosphere;
参考文献
Dinca, Emanuela; Hartmann, Philip; Smrcek, Jakub; Dix, Ina; Jones, Peter G.; Jahn, Ullrich
European Journal of Organic Chemistry, 2012 , # 24 p. 4461 - 4482
反应条件
water; tin(IV) chloride in 1,4-dioxane T=20 - 140°C; 3 h; AutoclaveInert atmosphere;
参考文献
Yamaguchi, Sho; Motokura, Ken; Sakamoto, Yasuharu; Miyaji, Akimitsu; Baba, Toshihide
Chemical Communications, 2014 , vol. 50, # 35 p. 4600 - 4602
反应条件
SnCl4*5H2O in water; acetonitrile T=59.84°C; 2 h;
参考文献
ACS Catalysis, , vol. 3, # 8 p. 1786 - 1800
反应条件
water; tin(IV) chloride in 1,4-dioxane T=20 - 140°C; 3 h; AutoclaveInert atmosphere;
参考文献
Yamaguchi, Sho; Motokura, Ken; Sakamoto, Yasuharu; Miyaji, Akimitsu; Baba, Toshihide
Chemical Communications, 2014 , vol. 50, # 35 p. 4600 - 4602
