4-甲氧基苯肼盐酸盐合成路线

参考文献

Demir, Ayhan S.; Reis, Oemer; Emrullahoglu, Mustafa
Tetrahedron, 2002 , vol. 58, # 40 p. 8055 - 8058

19501-58-74-甲氧基苯肼盐酸盐

19802-60-9

参考文献

Zhang, Xuqing; Li, Xiaojie; Allan, George F.; Musto, Amy; Lundeen, Scott G.; Sui, Zhihua
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 12 p. 3233 - 3237

19501-58-74-甲氧基苯肼盐酸盐+

104-83-64-氯氯苄

20955-94-6N-(4-氯苄基)-n-(4-甲氧基苯基)肼盐酸盐

参考文献

Riendeau, Denis; Aspiotis, Renee; Ethier, Diane; Gareau, Yves; Grimm, Erich L.; Guay, Jocelyne; Guiral, Sebastien; Juteau, Helene; Mancini, Joseph A.; Methot, Nathalie; Rubin, Joel; Friesen, Richard W.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 14 p. 3352 - 3355

367-57-7三氟乙酰丙酮+

19501-58-74-甲氧基苯肼盐酸盐

218632-10-11-(4-甲氧基苯基)-5-甲基-3-(三氟甲基)-1H-吡唑

参考文献

DuPont Pharmaceuticals Company
Patent: US5998424 A1, 1999 ;
US 5998424 A

367-57-7三氟乙酰丙酮+

19501-58-74-甲氧基苯肼盐酸盐

218632-10-11-(4-甲氧基苯基)-5-甲基-3-(三氟甲基)-1H-吡唑+

515845-28-0

参考文献

Pruitt, James R.; Pinto, Donald J. P.; Galemmo Jr., Robert A.; Alexander, Richard S.; Rossi, Karen A.; Wells, Brian L.; Drummond, Spencer; Bostrom, Lori L.; Burdick, Debra; Bruckner, Robert; Chen, Haiying; Smallwood, Angela; Wong, Pancras C.; Wright, Matthew R.; Bai, Steven; Luettgen, Joseph M.; Knabb, Robert M.; Lam, Patrick Y. S.; Wexler, Ruth R.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5298 - 5315

19501-58-74-甲氧基苯肼盐酸盐

218631-48-21-(4-甲氧基苯基)-3-(三氟甲基)-1H-吡唑-5-羧酸

参考文献

Pruitt, James R.; Pinto, Donald J. P.; Galemmo Jr., Robert A.; Alexander, Richard S.; Rossi, Karen A.; Wells, Brian L.; Drummond, Spencer; Bostrom, Lori L.; Burdick, Debra; Bruckner, Robert; Chen, Haiying; Smallwood, Angela; Wong, Pancras C.; Wright, Matthew R.; Bai, Steven; Luettgen, Joseph M.; Knabb, Robert M.; Lam, Patrick Y. S.; Wexler, Ruth R.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5298 - 5315

19501-58-74-甲氧基苯肼盐酸盐+

333-20-0硫氰化钾+

2114-00-32-溴苯丙酮

191349-37-81,3-二氢-1-[(4-甲氧基苯基)氨基]-4-甲基-5-苯基-2H-咪唑-2-硫酮

参考文献

Schantl, Joachim G.; Lagoja, Irene M.
Heterocycles, 1997 , vol. 45, # 4 p. 691 - 700

19501-58-74-甲氧基苯肼盐酸盐+

18931-60-71-(4-氯苯基)-4,4,4-三氟丁烷-1,3-二酮

188817-13-25-(4-氯苯基)-1-(4-甲氧基苯基)-3-(三氟甲基)-1H-吡唑

参考文献

Penning, Thomas D.; Talley, John J.; Bertenshaw, Stephen R.; Carter, Jeffery S.; Collins, Paul W.; Docter, Stephen; Graneto, Matthew J.; Lee, Len F.; Malecha, James W.; Miyashiro, Julie M.; Rogers, Roland S.; Rogier; Yu, Stella S.; Anderson, Gary D.; Burton, Earl G.; Cogburn, J. Nita; Gregory, Susan A.; Koboldt, Carol M.; Perkins, William E.; Seibert, Karen; Veenhuizen, Amy W.; Zhang, Yan Y.; Isakson, Peter C.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 9 p. 1347 - 1365

19501-58-74-甲氧基苯肼盐酸盐+

82874-96-22-(甲氧基亚胺)-4-氧代-戊酸乙酯

218632-36-11-(4-甲氧基苯基)-3-甲基-1H-吡唑-5-羧酸乙酯

参考文献

Pruitt, James R.; Pinto, Donald J. P.; Galemmo Jr., Robert A.; Alexander, Richard S.; Rossi, Karen A.; Wells, Brian L.; Drummond, Spencer; Bostrom, Lori L.; Burdick, Debra; Bruckner, Robert; Chen, Haiying; Smallwood, Angela; Wong, Pancras C.; Wright, Matthew R.; Bai, Steven; Luettgen, Joseph M.; Knabb, Robert M.; Lam, Patrick Y. S.; Wexler, Ruth R.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 25 p. 5298 - 5315

19501-58-74-甲氧基苯肼盐酸盐+

615-79-2乙酰丙酮酸乙酯

126068-76-61-(4-甲氧基-苯基)-5-甲基-1H-吡唑-3-羧酸乙酯+

218632-36-11-(4-甲氧基苯基)-3-甲基-1H-吡唑-5-羧酸乙酯

参考文献

Athersys, Inc.
Patent: US2007/197526 A1, 2007 ;
Location in patent: Page/Page column 14; 15; 26; 27 ;
US 20070197526 A1