5-丁基-1h,3h,5h-嘧啶-2,4,6-三酮合成路线 (共 10 条)
反应条件
sodium ethanolate in ethanol 6 h; Heating;
参考文献
Toth; Makleit
Acta Chimica Academiae Scientiarum Hungaricae, 1981 , vol. 107, # 2 p. 139 - 145
反应条件
sodium cyanoborohydride in acetic acid 1 h;
参考文献
Nutaitis, Charles F.; Schultz, Rose Ann; Obaza, Judy; Smith, Francis X.
Journal of Organic Chemistry, 1980 , vol. 45, # 23 p. 4606 - 4608
反应条件
methanol; palladium on activated charcoal Hydrogenation;
参考文献
US2446503 , ;
Festschrift E. Barell <Basel 1946> S. 435, 440, 443
反应条件
methanol; palladium on activated charcoal Hydrogenation;
参考文献
US2446503 , ;
Festschrift E. Barell <Basel 1946> S. 435, 440, 443
反应条件
T=30°C; Rate constant;
参考文献
Journal of the Chemical Society, , p. 1622
反应条件
T=30°C; Rate constant;
参考文献
Journal of the Chemical Society, , p. 769,772
反应条件
sodium hydroxide T=20°C;
参考文献
Volwiler
Journal of the American Chemical Society, 1925 , vol. 47, p. 2239
反应条件
sodium hydroxide; copper(II) sulfate
参考文献
Chandanayingyong
J. pharm. Assoc. Siam, 1948 , vol. 1, # 5 p. 4,12
参考文献
Doran; Shonle
Journal of the American Chemical Society, 1938 , vol. 60, p. 2880
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E. Lilly and Co.
Patent: US2250422 , 1938 ;
反应条件
1: 53 percent / 87percent aq. H3PO4, POCl3 / 2 h / 90 - 100 °C
2: 83 percent / H2, 2N aq. NaOH / 10percent Pd/C / 2068.6 Torr
View Scheme
参考文献
Su; Watanabe; Schinazi; Fox
Journal of Medicinal Chemistry, 1986 , vol. 29, # 1 p. 151 - 154