hydrogenchloride

hydrogenchloride 4 h; Heating;

1.1: NaH / dimethylformamide; various solvent(s) / 0.5 h / 20 °C 1.2: 80 percent / dimethylformamide; various solvent(s) / 7 h / 20 - 60 °C 2.1: NaOH / methanol / 20 h / 20 °C 3.1: p-xylene / 2 h / Heating 4.1: 75 percent / aq. HCl / 4 h / Heating View Scheme

1: NaOH / methanol / 20 h / 20 °C 2: p-xylene / 2 h / Heating 3: 75 percent / aq. HCl / 4 h / Heating View Scheme

1.1: 74.5 percent / conc. HCl / 65 °C 2.1: NaH / dimethylformamide; various solvent(s) / 0.5 h / 20 °C 2.2: 80 percent / dimethylformamide; various solvent(s) / 7 h / 20 - 60 °C 3.1: NaOH / methanol / 20 h / 20 °C 4.1: p-xylene / 2 h / Heating 5.1: 75 percent / aq. HCl / 4 h / Heating View Scheme

1: 1.) thionyl chloride / 1.) -10 deg C, 30 min, 2.) RT, 2 d 2: 69 percent / ethanol; H2O / 5 h / 80 °C 3: 74 percent / tetrahydrofuran / 1 h / 70 °C 4: 75 percent / 5 N NaOH / methanol / 1 h / 100 °C 5: 65 percent / diphenyl phosphorazidate (DPPA), NEt3 / dimethylformamide / 1.) 0 deg C, 1 h, 2.) 20 deg C, 12 h 6: 82 percent / 1 N HCl / ethyl acetate / 1 h / 80 °C View Scheme

phenylalanine ammonia-lyase in various solvent(s) T=30°C; pH=8.8; Enzyme kinetics;

phenylalanine ammonia-lyase in various solvent(s) T=30°C; pH=8.8; Enzyme kinetics;