1-(4-氯苯基)-乙酮肟合成路线 （共 37 条）
反应条件
S4N4*SbCl5 in toluene T=60°C; Rearrangement; Beckmann rearrangement; 1 h;
参考文献
Heterocycles, , vol. 50, # 1 p. 147 - 157
反应条件
hydrogenchloride; sodium hydroxide; sodium in ethanol; benzene
参考文献
U.S. Philips Corporation
Patent: US4071686 A1, 1978 ;
反应条件
(i) nBuLi, THF, (ii) /BRN= 1900390/, aq. HCl; Multistep reaction;
参考文献
Griffiths,J.S. et al.
Journal of the Chemical Society [Section] C: Organic, 1971 , p. 974 - 975
反应条件
1: With (Ph)2SiH2; silver trifluoromethanesulfonate in tetrahydrofuran T=20°C; 25 h; 2: With hydrogenchloride in tetrahydrofuran; methanol Further stages. Title compound not separated from byproducts.;
参考文献
Takei; Nishibayashi; Ishii; Mizobe; Uemura; Hidai
Chemical Communications, 2001 , # 22 p. 2360 - 2361
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide / 24 h / Cooling with ice 1.2: 20 °C 2.1: C9H16BNO / tetrahydrofuran / 24 h / 20 °C 2.2: 24 h / Reflux View Scheme
参考文献
Pakulski, Marcin M.; Mahato, Sanjit K.; Bosiak, Mariusz J.; Krzeminski, Marek P.; Zaidlewicz, Marek
Tetrahedron Asymmetry, 2012 , vol. 23, # 9 p. 716 - 721
反应条件
1: hydrazine hydrate / bis-(2-hydroxy-ethyl) ether / Heating 2: KOH / bis-(2-hydroxy-ethyl) ether / 3.5 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 36, # 15 p. 2183 - 2187
参考文献
Acta Poloniae Pharmaceutica - Drug Research, , vol. 68, # 2 p. 231 - 236
反应条件
p-toluenesulfonyl chloride in acetonitrile Beckmann rearrangement; 2 h; Inert atmosphereReflux;
参考文献
Maia, Angelamaria; Albanese, Domenico C.M.; Landini, Dario
Tetrahedron, 2012 , vol. 68, # 7 p. 1947 - 1950
反应条件
S4N4*SbCl5 in toluene T=60°C; Rearrangement; Beckmann rearrangement; 1 h;
参考文献
Heterocycles, , vol. 50, # 1 p. 147 - 157
反应条件
silica gel; caesium carbonate; 1-(toluene-p-sulphonyl)imidazole in N,N-dimethyl-formamide Beckmann rearrangement; 2 h; Reflux;
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 185, # 8 p. 1658 - 1671
