Boc-γ-L-二高苯丙氨酸合成路线 （共 9 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate Hydrogenation; P=2327.17 Torr; 3 h;
参考文献
Canadian Journal of Chemistry, , vol. 78, # 6 p. 800 - 808
反应条件
sodium hydroxide in water; acetone T=22°C; 0.5 h;
参考文献
Tetrahedron, , vol. 53, # 38 p. 12867 - 12874
反应条件
sodium hydroxide in ethanol T=0°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 11 p. 1541 - 1546
反应条件
1: Et3N / CH2Cl2 / 0 °C 2: 1.) DBU, 2.) H2 / 2.) 10 percent Pd/C / 1.) CH3CN, 2.) EtOH 3: 1 N aq. NaOH / ethanol / 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 11 p. 1541 - 1546
反应条件
1.1: DIBAL-H / toluene / 0.5 h / -78 °C 1.2: toluene; methanol / 12 h / -78 °C 2.1: 10 percent aq. NaOH / methanol / 18 h / 20 °C 3.1: 87 percent / H2 / 10 percent Pd/C / ethyl acetate / 3 h / 2327.17 Torr View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 78, # 6 p. 800 - 808
反应条件
1: 10 percent aq. NaOH / methanol / 18 h / 20 °C 2: 87 percent / H2 / 10 percent Pd/C / ethyl acetate / 3 h / 2327.17 Torr View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 78, # 6 p. 800 - 808
反应条件
1: DMAP, DCC / CH2Cl2 / 12 h / 0 °C 2: AcOH, NaBH4 / CH2Cl2 / 8 h / -5 °C 3: 96 percent / toluene / 3 h / Heating 4: 86 percent / NaOH / acetone; H2O / 0.5 h / 22 °C View Scheme
参考文献
Tetrahedron, , vol. 53, # 38 p. 12867 - 12874
反应条件
1: 96 percent / toluene / 3 h / Heating 2: 86 percent / NaOH / acetone; H2O / 0.5 h / 22 °C View Scheme
参考文献
Tetrahedron, , vol. 53, # 38 p. 12867 - 12874
反应条件
1: AcOH, NaBH4 / CH2Cl2 / 8 h / -5 °C 2: 96 percent / toluene / 3 h / Heating 3: 86 percent / NaOH / acetone; H2O / 0.5 h / 22 °C View Scheme
参考文献
Tetrahedron, , vol. 53, # 38 p. 12867 - 12874
