1: NaOEt 2: 100 percent / aq. KOH / ethanol / 1 h / Ambient temperature 3: 67 percent / dimethylformamide / 1.5 h / Heating 4: 100 percent / H2, aq. HCl / 10 percent Pd/C / ethanol 5: 100 percent / 6 N HCl / 4 h / Heating 6: CuSO4, pH 9 / dioxane; H2O / 16 h / Ambient temperature 7: pH 12.5 / 20 h / Ambient temperature View Scheme

1: 100 percent / aq. KOH / ethanol / 1 h / Ambient temperature 2: 67 percent / dimethylformamide / 1.5 h / Heating 3: 100 percent / H2, aq. HCl / 10 percent Pd/C / ethanol 4: 100 percent / 6 N HCl / 4 h / Heating 5: CuSO4, pH 9 / dioxane; H2O / 16 h / Ambient temperature 6: pH 12.5 / 20 h / Ambient temperature View Scheme

1: 100 percent / H2, aq. HCl / 10 percent Pd/C / ethanol 2: 100 percent / 6 N HCl / 4 h / Heating 3: CuSO4, pH 9 / dioxane; H2O / 16 h / Ambient temperature 4: pH 12.5 / 20 h / Ambient temperature View Scheme

1: 67 percent / dimethylformamide / 1.5 h / Heating 2: 100 percent / H2, aq. HCl / 10 percent Pd/C / ethanol 3: 100 percent / 6 N HCl / 4 h / Heating 4: CuSO4, pH 9 / dioxane; H2O / 16 h / Ambient temperature 5: pH 12.5 / 20 h / Ambient temperature View Scheme

1: 100 percent / 6 N HCl / 4 h / Heating 2: CuSO4, pH 9 / dioxane; H2O / 16 h / Ambient temperature 3: pH 12.5 / 20 h / Ambient temperature View Scheme

pH 12.5 20 h; Ambient temperature; Yield given;