3-苄基-7-氰基-2,3,4,5-四氢-1H-苯二氮卓类合成路线 （共 3 条）
反应条件
1-methyl-pyrrolidin-2-one T=200°C; Substitution; 3.5 h;
参考文献
Hunt; Ding; Batorsky; Bednarz; Bhide; Cho; Chong; Chao; Gullo-Brown; Guo; Soong Hoon Kim; Lee; Leftheris; Miller; Mitt; Patel; Penhallow; Ricca; Rose; Schmidt; Slusarchyk; Vite; Manne
Journal of Medicinal Chemistry, 2000 , vol. 43, # 20 p. 3587 - 3595
反应条件
1: 91 percent / BH3*THF / tetrahydrofuran / 18 h / Heating 2: 80 percent / 1-methyl-2-pyrrolidinone / 3.5 h / 200 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 20 p. 3587 - 3595
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; Sulfonylation; 58 h;
参考文献
Hunt; Ding; Batorsky; Bednarz; Bhide; Cho; Chong; Chao; Gullo-Brown; Guo; Soong Hoon Kim; Lee; Leftheris; Miller; Mitt; Patel; Penhallow; Ricca; Rose; Schmidt; Slusarchyk; Vite; Manne
Journal of Medicinal Chemistry, 2000 , vol. 43, # 20 p. 3587 - 3595
