7-溴-3,4-二氢-1H-苯并[e][1,4]二氮杂卓-2,5-二酮合成路线 （共 5 条）
反应条件
1: With triethylamine in water T=20°C; 4 h; 2: With acetic acid T=140°C; 4.5 h;
参考文献
KUDOS PHARMACEUTICALS LIMITED
Patent: WO2008/23161 A1, 2008 ;
Location in patent: Page/Page column 118 ;
WO 2008/023161 A1
反应条件
bromine in acetic acid T=20°C; 3 h;
参考文献
Osman; El-Gendy; Omar; Wagdy
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 4 p. 871 - 874
反应条件
pyridine cyclocondensation; 7 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 25 p. 5241 - 5253
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 20 h; Heating;
参考文献
Osman; El-Gendy; Omar; Wagdy
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 4 p. 871 - 874
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
14 h; Heating;
参考文献
Osman; El-Gendy; Omar; Wagdy
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 4 p. 871 - 874
