6-甲氧基-7-硝基喹唑啉-4(3h)-酮合成路线 （共 6 条）
参考文献
Zeneca Limited
Patent: US6184225 B2, 2001 ;
反应条件
Formylation; Cyclization; 4.5 h; Heating;
参考文献
Hennequin, Laurent F.; Thomas, Andrew P.; Johnstone, Craig; Stokes, Elaine S. E.; Ple, Patrick A.; Lohmann, Jean-Jacques M.; Ogilvie, Donald J.; Dukes, Mike; Wedge, Steve R.; Curwen, Jon O.; Kendrew, Jane; Lambert-Van Der Brempt, Christine
Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5369 - 5389
反应条件
1: 92 percent / aq. HCl / 3 h / Heating 2: 67 percent / 4.5 h / Heating View Scheme
参考文献
Dewar
Journal of the Chemical Society, 1944 , p. 619,622
反应条件
1: acetic acid; nitric acid / -5 °C 2: potassium permanganate; magnesium sulfate; water 3: aqueous hydrochloric acid View Scheme
参考文献
Dewar
Journal of the Chemical Society, 1944 , p. 619,622
反应条件
1: potassium permanganate; magnesium sulfate; water 2: aqueous hydrochloric acid View Scheme
参考文献
Dewar
Journal of the Chemical Society, 1944 , p. 619,622
反应条件
1: POCl3; PCl5
2: palladium/CaCO3; methanol / Hydrogenation.und Behandeln des Reaktionsprodukts mit K3<Fe(CN)6> in wss.KOH
View Scheme
参考文献
Elderfield; Dodd; Gensler
Journal of Organic Chemistry, 1947 , vol. 12, p. 393,399
