4-Boc-哌嗪-1-硫酰胺合成路线 （共 4 条）
反应条件
1: in tetrahydrofuran T=20°C; 1 h; 2: With ammonia in tetrahydrofuran; water T=20°C; 12 h;
参考文献
NV reMYND
Patent: US2010/197703 A1, 2010 ;
Location in patent: Page/Page column 77 ;
反应条件
1: in tetrahydrofuran T=20 - 55°C; 3 h; 2: With ammonia in tetrahydrofuran; methanol T=55°C; 16 h;
参考文献
WO2005/66180 A1, ;
Page/Page column 71 ;
WO 2005/066180 A1
反应条件
1: Et3N / tetrahydrofuran / 0 - 20 °C 2: NH3 / ethanol / 16 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 16 p. 4296 - 4299
反应条件
4-methyl-morpholine in ethanol 2.5 h; Heating / reflux;
参考文献
MEDIVIR AB
Patent: WO2007/6714 A1, 2007 ;
Location in patent: Page/Page column 90 ;
