1.1: samarium diiodide / tetrahydrofuran / 2.17 h / -78 °C / Inert atmosphere 1.2: Inert atmosphere 2.1: hydrogenchloride / 1,4-dioxane / 0.5 h / 20 °C View Scheme

1: lithium tert-butylate / tetrahydrofuran 2: [copperl(II)(1,1,1,5,5,5-hexafluoroacetylacetonate)2] monohydrate / toluene / 1 h / 150 °C / Inert atmosphere View Scheme

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 1.5 h / -70 °C / |Inert atmosphere 1.2: 4.5 h / -70 °C / |Inert atmosphere 2.1: hydrogenchloride / water; ethyl acetate / 10 h / 20 °C 3.1: triethylamine / dichloromethane / 20 °C / |Inert atmosphere 4.1: pyridinium p-toluenesulfonate / toluene / 4.33 h / 90 - 100 °C / |Inert atmosphere 5.1: hydrogen; palladium(II) oxide hydrate / methanol / 1 h / 20 °C / 1034.32 Torr / |Inert atmosphere 6.1: dicyclohexyl-carbodiimide; 4-(N,N-dimethlyamino)pyridine; toluene-4-sulfonic acid / dichloromethane / 20 °C / |Inert atmosphere 7.1: acetyl chloride / tetrahydrofuran; methanol / 2 h / 0 °C / |Inert atmosphere View Scheme

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 1.5 h / -70 °C / |Inert atmosphere 1.2: 4.5 h / -70 °C / |Inert atmosphere 2.1: hydrogenchloride / water; ethyl acetate / 10 h / 20 °C 3.1: triethylamine / dichloromethane / 20 °C / |Inert atmosphere 4.1: pyridinium p-toluenesulfonate / toluene / 4.33 h / 90 - 100 °C / |Inert atmosphere 5.1: hydrogen; palladium(II) oxide hydrate / methanol / 1 h / 20 °C / 1034.32 Torr / |Inert atmosphere View Scheme

1: magnesium / tetrahydrofuran; dichloromethane / 1 h / -50 - 20 °C 2: hydrogenchloride / water / 20 °C View Scheme