1-苄基-1,2,3,4-四氢异喹啉合成路线 （共 40 条）
反应条件
hydrogenchloride 23 h; Heating;
参考文献
Seebach, Dieter; Lohmann, Jean-Jacques; Syfrig, Max A.; Yoshifuji, Masaaki
Tetrahedron, 1983 , vol. 39, # 12 p. 1963 - 1974
反应条件
1: 88 percent / pyridine / 3 h / 0 °C 2: 69 percent / tetramethylethylenediamine; t-butyllithium / tetrahydrofuran / 2 h / -78 °C 3: 36 percent / hydrochloric acid / H2O / 24 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 42, # 4 p. 647 - 659
反应条件
1: 91 percent 2: 83 percent / LiAlH4 3: 76 percent / 1,4-dicyanobenzene / acetonitrile; H2O / Irradiation View Scheme
参考文献
Journal of the American Chemical Society, , vol. 117, # 2 p. 660 - 669
反应条件
1: 83 percent / LiAlH4 2: 76 percent / 1,4-dicyanobenzene / acetonitrile; H2O / Irradiation View Scheme
参考文献
Journal of the American Chemical Society, , vol. 117, # 2 p. 660 - 669
反应条件
hydrazine in ethanol; acetic acid T=53°C; 12 h; Yield given;
参考文献
Tetrahedron Letters, , vol. 22, # 51 p. 5115 - 5118
反应条件
2: P2O5 / toluene / Heating 3: NaBH4; EtOH / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 15 p. 1669 - 1671
反应条件
hydrogenchloride in water 24 h; Heating;
参考文献
Al-Hiari, Yusuf M.; Bennett, Stephen J.; Cox, Brian; Davies, Robert J.; Khalaf, Abedawn I.; Waigh, Roger D.; Worsley, Alan J.
Journal of Heterocyclic Chemistry, 2005 , vol. 42, # 4 p. 647 - 659
反应条件
sodium tetrahydroborate; trifluoromethanesulphonyl fluoride; tetraethylammonium cyanide Yield given. Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 115, # 25 p. 11863 - 11873
反应条件
hydrazine hydrate; acetic acid in ethanol T=60°C; 12 h;
参考文献
Singh, Kamal Nain; Singh, Paramjit; Kaur, Amarjit
Synthetic Communications, 2006 , vol. 36, # 22 p. 3339 - 3343
反应条件
1: diethyl cyanophosphate, Et3N / dimethylformamide / 4 h 2: POCl3, P2O5 / 2 h / Heating 3: NaBH4 / ethanol / 16 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 6 p. 1242 - 1248
