4-二甲胺基丁醛缩二甲醇合成路线 （共 14 条）
反应条件
iodine; magnesium in benzene 5.25 - 6.33333 h; Heating / reflux;
参考文献
NATCO PHARMA LIMITED
Patent: WO2003/101931 A2, 2003 ;
Location in patent: Page 11 ;
反应条件
potassium carbonate in methanol T=60°C; 5 h;
参考文献
Hassan, Maizom; Morimoto, Sachiko; Murakami, Hiroyuki; Ichiyanagi, Tsuyoshi; Mori, Nobuhiro
Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 6 p. 1439 - 1446
反应条件
in water 1.) r.t., 15 min, 2.) 62 deg C, 1 h;
参考文献
Chen; Senanayake; Bill; Larsen; Verhoeven; Reider
Journal of Organic Chemistry, 1994 , vol. 59, # 13 p. 3738 - 3741
反应条件
sulfuric acid 2 h; Heating;
参考文献
Chen; Senanayake; Bill; Larsen; Verhoeven; Reider
Journal of Organic Chemistry, 1994 , vol. 59, # 13 p. 3738 - 3741
反应条件
sulfuric acid 2 h; Heating;
参考文献
Chen; Senanayake; Bill; Larsen; Verhoeven; Reider
Journal of Organic Chemistry, 1994 , vol. 59, # 13 p. 3738 - 3741
反应条件
sulfuric acid 2 h; Heating;
参考文献
Chen; Senanayake; Bill; Larsen; Verhoeven; Reider
Journal of Organic Chemistry, 1994 , vol. 59, # 13 p. 3738 - 3741
反应条件
sulfuric acid 2 h; Heating;
参考文献
Chen; Senanayake; Bill; Larsen; Verhoeven; Reider
Journal of Organic Chemistry, 1994 , vol. 59, # 13 p. 3738 - 3741
反应条件
sulfuric acid 2 h; Heating;
参考文献
Chen; Senanayake; Bill; Larsen; Verhoeven; Reider
Journal of Organic Chemistry, 1994 , vol. 59, # 13 p. 3738 - 3741
反应条件
1: With hydrogenchloride in water T=25 - 30°C; 4 h; 2: With phosphoric acid triethylester in chloroform T=25 - 30°C; 4 h;
参考文献
POTLURI, Ramesh, Babu; HARIHARAKRISHNAN, Venkata, Subramanian; TADIMALLA, Venkata, Srihari; KODALI, Hari, Prasad; GOTTIMUKKALA, Venkata, Mallaparaju
Patent: WO2004/99141 A1, 2004 ;
Location in patent: Page 10-12 ;
反应条件
hydrogenchloride in water T=0 - 75°C; 3 - 4 h; Product distribution / selectivity;
参考文献
WO2006/53116 A2, ;
Page/Page column 10-11; 12 ;
