(3-溴-吡啶-2-基)-乙酸乙酯合成路线 (共 2 条)
反应条件
lithium diisopropyl amide 1.) THF, cyclohexane, Et2O, 5 min, 2.) THF, cyclohexane, Et2O, 1 h; Yield given. Multistep reaction;
参考文献
Bremner; Dunn; Wilson; Sturrock; Wishart
Synthesis, 1997 , # 8 p. 949 - 952
反应条件
potassium phosphate; palladium diacetate; tri-cyclo-hexyl-phosphine in water; toluene T=100°C; 24 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2012/115863 A1, 2012 ;
Location in patent: Page/Page column 52-53 ;